Transition-Metal-Free Synthesis of C3-Arylated Benzofurans from Benzothiophenes and Phenols was written by Yang, Kevin;Pulis, Alexander P.;Perry, Gregory J. P.;Procter, David J.. And the article was included in Organic Letters in 2018.COA of Formula: C8H5BrS This article mentions the following:
A transition-metal-free synthesis of benzofurans from benzothiophenes and phenols that exploits the unique reactivity of sulfoxides, is reported. Through a sequence involving an interrupted Pummerer reaction and [3,3] sigmatropic rearrangement, phenols can be combined with readily accessible yet synthetically unexplored benzothiophene S-oxides to provide C3-arylated benzofuran products. The products from this approach can undergo subsequent functionalization to gain access to a range of important benzofuran derivatives In the experiment, the researchers used many compounds, for example, 4-Bromobenzo[b]thiophene (cas: 5118-13-8COA of Formula: C8H5BrS).
4-Bromobenzo[b]thiophene (cas: 5118-13-8) belongs to benzothiophene derivatives. Benzothiophene finds use in research as a starting material for the synthesis of larger, usually bioactive structures. It is found within the chemical structures of pharmaceutical drugs such as zileuton, raloxifene, and sertaconazole, and also BTCP.COA of Formula: C8H5BrS
Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem