Day: February 22, 2023

Efficiency Enhancement of a Photocatalytic Decarbonylation of an Aminocyclopropenone by Benzothiophene Substitution was written by Mishiro, Kenji;Nomura, Mitsuki;Furuyama, Taniyuki;Kunishima, Munetaka. And the article was included in Journal of Organic Chemistry in 2021.Related Products of 1195-14-8 This article mentions the following:

To improve the efficiency of the photocatalytic decarbonylation of cyclopropenones, the effects of substituents on cyclopropenone were explored. A benzothiophene-substituted aminocyclopropenone exhibited significantly improved decarbonylation efficiency to produce the corresponding ynamine, which worked as a potent dehydration condensation agent. The benzothiophene derivative was applicable to the photocatalytic reaction in the presence of potential excited-state quenchers such as oxygen and anilines. The high catalyst sensitivity would be attributed to the involvement of triplet energy transfer reaction pathway, which was not observed in the reaction with previously reported aminocyclopropenones. In the experiment, the researchers used many compounds, for example, 2-Methylbenzo[b]thiophene (cas: 1195-14-8Related Products of 1195-14-8).

2-Methylbenzo[b]thiophene (cas: 1195-14-8) belongs to benzothiophene derivatives. Benzothiophenes are valuable heterocycles that are widely used in medicines, agrochemicals, and materials science. It is found within the chemical structures of pharmaceutical drugs such as zileuton, raloxifene, and sertaconazole, and also BTCP.Related Products of 1195-14-8

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Gold(I)-Catalyzed Highly Diastereo- and Enantioselective Constructions of Bicyclo[3.2.1]oct-6-ene Frameworks via (4 + 3)-Cycloadditions was written by Tanpure, Sudhakar Dattatray;Kuo, Tung-Chun;Cheng, Mu-Jeng;Liu, Rai-Shung. And the article was included in ACS Catalysis in 2022.COA of Formula: C13H10OS This article mentions the following:

A one-pot construction of bicyclo[3.2.1]oct-6-ene frameworks involved gold-catalyzed (4 + 3)-cycloadditions between 2-(1-alkynyl)-2-alken-1-ones and substituted cyclopentadienes; diastereoselectivity (dr >25:1) and enantioselectivity (up to 99.9% ee) were achieved with a chiral gold catalyst. DFT calculations suggested a three-step ionic mechanism for the cycloadditions of gold-containing 1,3-dipoles with cyclopentadienes, in which an exo-spatial arrangement was preferable. In the experiment, the researchers used many compounds, for example, 3-Phenyl-1-(thiophen-2-yl)prop-2-en-1-one (cas: 3988-77-0COA of Formula: C13H10OS).

3-Phenyl-1-(thiophen-2-yl)prop-2-en-1-one (cas: 3988-77-0) belongs to benzothiophene derivatives. Benzothiophene is a fused ring compound of thiophene ring and benzene ring, which is an important class of heterocycles with advantageous structures. Due to its aromaticity, thiophenes do not exhibit the same properties as conventional thioethers.COA of Formula: C13H10OS

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Modification of mechanical properties and resolution of printed stereolithographic objects through RAFT agent incorporation was written by Green, Brian J.;Guymon, C. Allan. And the article was included in Additive Manufacturing in 2019.Reference of 7128-64-5 This article mentions the following:

In this work, we incorporate a reversible addition-fragmentation chain transfer (RAFT) agent into a glassy acrylate formulation to modify mech. properties and improve resolution of objects printed using digital light processing (DLP) stereolithog. (SL). Incorporating a small amount of a trithiocarbonate RAFT agent into the formulation leads to increased elongation and toughness accompanied by a small decrease in tensile modulus. To determine anisotropic properties of DLP SL, samples were printed in “horizontal” or “vertical” directions, where the long axis of the sample was printed in the x-axis or z-axis, resp. RAFT samples printed in a vertical orientation exhibit a higher modulus than non-RAFT controls prior to post-cure in addition to a similar modulus with increased toughness upon UV post-cure due to the living/controlled nature of RAFT polymerization The RAFT formulation allows objects to be printed with significantly better fidelity than non-RAFT formulations, even when a radical scavenger is incorporated to mimic reaction rates observed from the RAFT formulation. Addnl., the RAFT agent significantly increases the critical energy parameter determined from the SL working curve, indicating an increase in gel point conversion. This work demonstrates the benefits of using controlled/living polymerization in a highly crosslinked acrylate system to improve toughness, modify anisotropic properties, and print high-fidelity features with enhanced properties in 3D printed materials. In the experiment, the researchers used many compounds, for example, 2,5-Bis(5-(tert-butyl)benzo[d]oxazol-2-yl)thiophene (cas: 7128-64-5Reference of 7128-64-5).

2,5-Bis(5-(tert-butyl)benzo[d]oxazol-2-yl)thiophene (cas: 7128-64-5) belongs to benzothiophene derivatives. Benzothiophene is used as starting material for the synthesis of bioactive molecules. The core structure is a part of various pharmaceutical substances and natural products. It is found within the chemical structures of pharmaceutical drugs such as raloxifene, zileuton, sertaconazole, and also BTCP.Reference of 7128-64-5

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Lattice-Matched Epitaxial Growth of Organic Heterostructures for Integrated Optoelectronic Application was written by Zhang, Yi;Liao, Qing;Wang, Xinguo;Yao, Jiannian;Fu, Hongbing. And the article was included in Angewandte Chemie, International Edition in 2017.Computed Properties of C26H26N2O2S This article mentions the following:

Development of nanowire photonics requires integration of different nanowire components into highly ordered functional heterostructures. A sequential self-assembly of binary mol. components into branched nanowire heterostructures (BNHs) via lattice-matched epitaxial growth is reported, in which the microribbon backbone of 2,5-Bis(5-tert-butyl-2-benzoxazolyl)thiophene (BBOT) functions as blue-emitting microlaser source to pump the nanowire branches of BODIPY. By constructing Au electrodes on both branch sides and measuring the photocurrent in them, the integration of an organic laser and a power meter in a single device is realized. This work provides a new insight into the integration of 1D organic nanostructures into BNHs for realizing organic multifunctional photonic devices. In the experiment, the researchers used many compounds, for example, 2,5-Bis(5-(tert-butyl)benzo[d]oxazol-2-yl)thiophene (cas: 7128-64-5Computed Properties of C26H26N2O2S).

2,5-Bis(5-(tert-butyl)benzo[d]oxazol-2-yl)thiophene (cas: 7128-64-5) belongs to benzothiophene derivatives. Benzothiophene is relatively a stable molecule. The core structure is a part of various pharmaceutical substances and natural products. Its aromaticity makes it relatively stable, although as a heterocycle, it has reactive sites which allow for functionalization.Computed Properties of C26H26N2O2S

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Prediction of Collision Cross Section Values: Application to Non-Intentionally Added Substance Identification in Food Contact Materials was written by Song, Xue-Chao;Dreolin, Nicola;Damiani, Tito;Canellas, Elena;Nerin, Cristina. And the article was included in Journal of Agricultural and Food Chemistry in 2022.Application In Synthesis of 2,5-Bis(5-(tert-butyl)benzo[d]oxazol-2-yl)thiophene This article mentions the following:

The synthetic chems. in food contact materials can migrate into food and endanger human health. In this study, the traveling wave collision cross section in nitrogen values of more than 400 chems. in food contact materials were exptl. derived by traveling wave ion mobility spectrometry. A support vector machine-based collision cross section (CCS) prediction model was developed based on CCS values of food contact chems. and a series of mol. descriptors. More than 92% of protonated and 81% of sodiated adducts showed a relative deviation below 5%. Median relative errors for protonated and sodiated mols. were 1.50 and 1.82%, resp. The model was then applied to the structural annotation of oligomers migrating from polyamide adhesives. The identification confidence of 11 oligomers was improved by the direct comparison of the exptl. data with the predicted CCS values. Finally, the challenges and opportunities of current machine-learning models on CCS prediction were also discussed. In the experiment, the researchers used many compounds, for example, 2,5-Bis(5-(tert-butyl)benzo[d]oxazol-2-yl)thiophene (cas: 7128-64-5Application In Synthesis of 2,5-Bis(5-(tert-butyl)benzo[d]oxazol-2-yl)thiophene).

2,5-Bis(5-(tert-butyl)benzo[d]oxazol-2-yl)thiophene (cas: 7128-64-5) belongs to benzothiophene derivatives. Functionalized benzothiophenes are important constructs found in molecules with wide ranging biological activity and in organic materials. Its aromaticity makes it relatively stable, although as a heterocycle, it has reactive sites which allow for functionalization.Application In Synthesis of 2,5-Bis(5-(tert-butyl)benzo[d]oxazol-2-yl)thiophene

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Copper-Catalyzed Direct Trifluoro- and Perfluoroalkylselenolations of Boronic Acids with a Shelf-Stable Family of Reagents was written by Glenadel, Quentin;Ghiazza, Clement;Tlili, Anis;Billard, Thierry. And the article was included in Advanced Synthesis & Catalysis in 2017.Formula: C8H7BO2S This article mentions the following:

Herein the copper-catalyzed direct perfluoroalkylselenolation of aryl- and vinylboronic acids is described for the first time. The key to success is the design of new shelf-stable perfluoroalkylselenolating reagents, namely perfluoroalkyl tolueneselenosulfonates. The reaction occurs at room temperature in the presence of com. available catalyst and ligand in catalytic quantities. In the experiment, the researchers used many compounds, for example, Benzo[b]thiophen-3-ylboronic acid (cas: 113893-08-6Formula: C8H7BO2S).

Benzo[b]thiophen-3-ylboronic acid (cas: 113893-08-6) belongs to benzothiophene derivatives. Benzothiophene is relatively a stable molecule. The electrophilic substitution of benzothiophene systems is much less regioselective than that of indoles. It is found within the chemical structures of pharmaceutical drugs such as raloxifene, zileuton, and sertaconazole, and also BTCP.Formula: C8H7BO2S

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Large Changes in Fluorescent Color and Intensity of Symmetrically Substituted Arylmaleimides Caused by Subtle Structure Modifications was written by Wang, Jingwei;Liu, Zhengde;Yang, Shuming;Lin, Youzhi;Lin, Zhenghuan;Ling, Qidan. And the article was included in Chemistry – A European Journal in 2018.Application In Synthesis of Benzo[b]thiophen-3-ylboronic acid This article mentions the following:

Herein we report on four diarylmaleimides based on 3- or 2-substituted benzothiophene (M3S or M2S) and benzofuran (M3O or M2O), which show very different emission properties: aggregation-caused quenching (ACQ), aggregation-induced emission (AIE), and dual-state strong emission (DSE) in both solution and solid states. Their emission color in the solid state can be adjusted from green-yellow into red. M2O displays strong red solid-state emission at 630 nm with a quantum yield of 46.3 %. Single-crystal X-ray diffraction anal. confirms that their large distinction in solid-state emission originates from their different packing structures: hydrogen-bonded organic frameworks (HOFs) for M3S, a staggered structure for M3O, J-aggregation for M2S, and weak H-aggregation for M2O. HOF of M3S and weak H-aggregation of M2O make them produce inverse-type piezochromic fluorescence: blueshifted “turn-on” and red shifted “turn-off” emission, resp. These results provide new insight in fluorescence manipulated by subtle structure modification. In the experiment, the researchers used many compounds, for example, Benzo[b]thiophen-3-ylboronic acid (cas: 113893-08-6Application In Synthesis of Benzo[b]thiophen-3-ylboronic acid).

Benzo[b]thiophen-3-ylboronic acid (cas: 113893-08-6) belongs to benzothiophene derivatives. Benzothiophene is relatively a stable molecule. The electrophilic substitution of benzothiophene systems is much less regioselective than that of indoles. It is also used in the manufacturing of dyes such as thioindigo.Application In Synthesis of Benzo[b]thiophen-3-ylboronic acid

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Synthesis and Biological Evaluation of a New Series of Pyrazolines as New Anticandidal Agents was written by Ozdemir, Ahmet;Altintop, Mehlika Dilek;Kaplancikli, Zafer Asim;Turan-Zitouni, Gulhan;Ciftci, Gulsen Akalin;Demirci, Fatih. And the article was included in Pharmaceutical Chemistry Journal in 2014.Product Details of 3988-77-0 This article mentions the following:

New pyrazoline derivatives bearing an oxadiazole moiety were synthesized via the reaction of 1-(chloroacetyl)-3-(2-furyl/thienyl)-5-aryl-2-pyrazolines with 5-substituted-1,3,4-oxadiazole-2(3H)-thiones in the presence of potassium carbonate. The pyrazolines were screened for their antifungal activity against various Candida species and compared with ketoconazole. Among these compounds, the most effective derivatives were evaluated for their cytotoxicity against NIH/3T3 cells. 2-({2-[5-(4-Bromophenyl)-3-(2-furyl)-4,5-dihydro-1H-pyrazol-1-yl]-2-oxoethyl}thio)-5-(2-cyclopentylethyl)-1,3,4-oxadiazole can be identified as the most potent antifungal agent against C. tropicalis due to its inhibitory effect on C. tropicalis and low toxicity to NIH/3T3 cells. In the experiment, the researchers used many compounds, for example, 3-Phenyl-1-(thiophen-2-yl)prop-2-en-1-one (cas: 3988-77-0Product Details of 3988-77-0).

3-Phenyl-1-(thiophen-2-yl)prop-2-en-1-one (cas: 3988-77-0) belongs to benzothiophene derivatives. Benzothiophene finds use in research as a starting material for the synthesis of larger, usually bioactive structures. It is also used in the manufacturing of dyes such as thioindigo.Product Details of 3988-77-0

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Sulfonylureas: a new class of cancer chemotherapeutic agents was written by Mohamadi, Fariborz;Spees, Michael M.;Grindey, Gerald B.. And the article was included in Journal of Medicinal Chemistry in 1992.Recommanded Product: 1795-01-3 This article mentions the following:

Sulofenur thiophene analogs, e.g. I (R = H, 5-Cl, 5-MeO, 4-Me, 5-Et; X = S, O, NH), were prepared from the corresponding heterocycle and ClSO₃H/NH₃/4-ClC₆H₄NCO or BuLi/SO₂/H₂NOSO₃H/4-ClC₆H₄NCO and tested against s.c. implanted 6C3HED lymphosarcoma. The spectrum of activity of I (R = MeO, X = S) in the HXGC3, VRC5, CX-1, and LX-1 cell lines is also presented. In the experiment, the researchers used many compounds, for example, 3-Ethylthiophene (cas: 1795-01-3Recommanded Product: 1795-01-3).

3-Ethylthiophene (cas: 1795-01-3) belongs to benzothiophene derivatives. Benzothiophene is used as starting material for the synthesis of bioactive molecules. The core structure is a part of various pharmaceutical substances and natural products. It is also used in the manufacturing of dyes such as thioindigo.Recommanded Product: 1795-01-3

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Ir(III)-Catalyzed Oxidative Annulation of Phenylglyoxylic Acids with Benzo[b]thiophenes was written by Wang, Zhigang;Yang, Mufan;Yang, Yudong. And the article was included in Organic Letters in 2018.SDS of cas: 5118-13-8 This article mentions the following:

An Ir(III)-catalyzed oxidative annulation of phenylglyoxylic acids with benzo[b]thiophenes for the construction of benzothieno[3,2-c][2]benzopyranones in one step is disclosed. Three C-H cleavages and C-C/C-O bond formations are involved in this reaction. This protocol features a relatively broad substrate scope, good functional group tolerance, good regioselectivities, mild reaction conditions, and scale-up synthesis. In the experiment, the researchers used many compounds, for example, 4-Bromobenzo[b]thiophene (cas: 5118-13-8SDS of cas: 5118-13-8).

4-Bromobenzo[b]thiophene (cas: 5118-13-8) belongs to benzothiophene derivatives. Benzothiophene finds use in research as a starting material for the synthesis of larger, usually bioactive structures. It is found within the chemical structures of pharmaceutical drugs such as raloxifene, zileuton, and sertaconazole, and also BTCP.SDS of cas: 5118-13-8

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem