Iso-anellated thienopyrroles. The chemistry of 5,6-dihydro-4H-thieno[2,3-c]pyrroles and 5H-thieno[2,3-c]pyrroles was written by Feijen, J.;Wynberg, Hans. And the article was included in Recueil des Travaux Chimiques des Pays-Bas in 1970.HPLC of Formula: 28686-90-0 This article mentions the following:
The ring-closure reaction of Me 2,3-bis(chloromethyl)thiophene-5-carboxylate with several primary amines gives a series of 4,6-dihydro-5H-thieno[2,3-c]pyrroles. Oxidation of some of these dihydro compounds, using aqueous H2O2 in methanol, furnishes the corresponding N-oxides. When the N atom possesses an aromatic substituent and the oxidation is carried out with aqueous H2O2 in formic acid, Meisenheimer rearrangement products instead of N-oxides are formed. The structure of one of the Meisenheimer products was elucidated by an independent synthesis of its degradation product. 5H-Thieno[2,3-c]pyrroles, such as I, are prepared by 3 sep. methods: (a) dehydration of the N-oxides; (b) autoxidation of the dihydrothieno[2,3-c]pyrroles; (c) dehydrogenation of the dihydro compounds with chloranil. In the experiment, the researchers used many compounds, for example, Methyl 4-methylthiophene-2-carboxylate (cas: 28686-90-0HPLC of Formula: 28686-90-0).
Methyl 4-methylthiophene-2-carboxylate (cas: 28686-90-0) belongs to benzothiophene derivatives. Functionalized benzothiophenes are important constructs found in molecules with wide ranging biological activity and in organic materials. Its aromaticity makes it relatively stable, although as a heterocycle, it has reactive sites which allow for functionalization.HPLC of Formula: 28686-90-0
Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem