Copper-mediated Chan-Evans-Lam N-arylation of 5-methylene-4-aryl-1,5-dihydro-2H-pyrrol-2-one derivatives was written by Almohaywi, Basmah;Iskander, George;Yu, Tsz Tin;Bhadbhade, Mohan;Black, David StC.;Kumar, Naresh. And the article was included in Tetrahedron Letters in 2018.Recommanded Product: 113893-08-6 This article mentions the following:
A simple and efficient procedure for the synthesis of N-aryl 5-methylene-4-aryl-1,5-dihydro-2H-pyrrol-2-one derivatives, e.g., I. has been developed through copper-mediated C-N bond formation. The synthetic protocol allows for versatile and robust C-N arylation with a range of readily available boronic acids under mild conditions. In the experiment, the researchers used many compounds, for example, Benzo[b]thiophen-3-ylboronic acid (cas: 113893-08-6Recommanded Product: 113893-08-6).
Benzo[b]thiophen-3-ylboronic acid (cas: 113893-08-6) belongs to benzothiophene derivatives. Benzothiophene is used as starting material for the synthesis of bioactive molecules. The core structure is a part of various pharmaceutical substances and natural products. It is found within the chemical structures of pharmaceutical drugs such as zileuton, raloxifene, and sertaconazole, and also BTCP.Recommanded Product: 113893-08-6
Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem