Enantioselective synthesis of acyclic monohydrosilanes by steric hindrance assisted C-H silylation was written by Mu, Delong;Pan, Shuqiong;Wang, Xiaoyu;Liao, Xiaoyun;Huang, Yong;Chen, Jiean. And the article was included in Chemical Communications (Cambridge, United Kingdom) in 2022.COA of Formula: C9H8OS This article mentions the following:
Herein, a rhodium-catalyzed desymmetrization of dihydrosilanes with heterocyclic compounds via intermol. dehydrogenative C-H silylation is developed. The strategy tolerates a variety of thianaphthene and thiophene derivatives, giving rise to a wide range of silicon-stereogenic acyclic monohydrosilanes. Several rare skeletons featuring bis-silicon-stereogenic centers were also designed to enhance the library’s diversity further. Preliminary mechanistic studies reveal that the surrounding spatial environment of the Si-center plays a crucial role in enabling intermol. C-H silylation preferentially. In the experiment, the researchers used many compounds, for example, 6-Methoxybenzo[b]thiophene (cas: 90560-10-4COA of Formula: C9H8OS).
6-Methoxybenzo[b]thiophene (cas: 90560-10-4) belongs to benzothiophene derivatives. Benzothiophene is relatively a stable molecule. The electrophilic substitution of benzothiophene systems is much less regioselective than that of indoles. The different substitution patterns in these heterocycles offer new opportunities for drug discovery and other applications in materials science.COA of Formula: C9H8OS
Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem