Enantioselective Hydroarylation or Hydroalkenylation of Benzo[b]thiophene 1,1-Dioxides with Organoboranes was written by Hu, Fangdong;Jia, Jie;Li, Ximing;Xia, Ying. And the article was included in Organic Letters in 2021.Recommanded Product: 6-Methoxybenzo[b]thiophene This article mentions the following:
An efficient protocol for the asym. hydroarylation and hydroalkenylation of benzo[b]thiophene 1,1-dioxides with organoboranes was developed. The combination of a rhodium(I) precatalyst and a chiral diene ligand constituted the catalytic system, which enabled the facile synthesis of 2,3-dihydrobenzo[b]thiophene 1,1-dioxides I [R = H, 5-Me, 7-Me, etc.; R1 = H, Me, Et, i-Pr; Ar = Ph, 2-naphthyl, 3-thienyl, (E)-styryl, etc.] in good yields with high enantioselectivities. The merging of this asym. hydroarylation with the downstream alkylations delivered 2,3-dihydrobenzo[b]thiophene 1,1-dioxides that contain two continuous quaternary stereocenters with high enantioselectivities in a diastereodivergent manner. In the experiment, the researchers used many compounds, for example, 6-Methoxybenzo[b]thiophene (cas: 90560-10-4Recommanded Product: 6-Methoxybenzo[b]thiophene).
6-Methoxybenzo[b]thiophene (cas: 90560-10-4) belongs to benzothiophene derivatives. Benzothiophenes are valuable heterocycles that are widely used in medicines, agrochemicals, and materials science. It has been used as a raw material for the synthesis of biologically active structures and is found in pharmaceuticals such as leukotriene synthesis inhibitors and antifungals, as well as in many natural products.Recommanded Product: 6-Methoxybenzo[b]thiophene
Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem