Hsiao, Chi Nung et al. published their research in Synthetic Communications in 1990 | CAS: 55219-11-9

Benzo[b]thiophene-2-carbonitrile (cas: 55219-11-9) belongs to benzothiophene derivatives. Benzothiophene is used as starting material for the synthesis of bioactive molecules. The core structure is a part of various pharmaceutical substances and natural products. Its aromaticity makes it relatively stable, although as a heterocycle, it has reactive sites which allow for functionalization.Computed Properties of C9H5NS

A practical synthesis of 2-carbonylbenzo[b]thiophenes was written by Hsiao, Chi Nung;Bhagavatula, Lakshmi;Pariza, Richard J.. And the article was included in Synthetic Communications in 1990.Computed Properties of C9H5NS This article mentions the following:

The sequential reduction and alkylation of 2-HSC6H4CO2H gave 2-RCH2SC6H4CH2OH [R = COMe, COPh, COCMe3, CO2Et, cyano, CH(OMe)2]. The oxidation and intramol. aldol condensation of the latter gave the title compounds I (same R). In the experiment, the researchers used many compounds, for example, Benzo[b]thiophene-2-carbonitrile (cas: 55219-11-9Computed Properties of C9H5NS).

Benzo[b]thiophene-2-carbonitrile (cas: 55219-11-9) belongs to benzothiophene derivatives. Benzothiophene is used as starting material for the synthesis of bioactive molecules. The core structure is a part of various pharmaceutical substances and natural products. Its aromaticity makes it relatively stable, although as a heterocycle, it has reactive sites which allow for functionalization.Computed Properties of C9H5NS

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem