Direct release of nitriles from solid phase was written by Hone, N. D.;Payne, L. J.;Tice, C. M.. And the article was included in Tetrahedron Letters in 2001.Product Details of 55219-11-9 This article mentions the following:
Cleavage conditions are described which allow resin-bound secondary amides to be liberated from Sieber or Rink resin as nitriles. The method was applied to the synthesis of a series of cyano biaryls. In the experiment, the researchers used many compounds, for example, Benzo[b]thiophene-2-carbonitrile (cas: 55219-11-9Product Details of 55219-11-9).
Benzo[b]thiophene-2-carbonitrile (cas: 55219-11-9) belongs to benzothiophene derivatives. Benzothiophenes are valuable heterocycles that are widely used in medicines, agrochemicals, and materials science. Due to its aromaticity, thiophenes do not exhibit the same properties as conventional thioethers.Product Details of 55219-11-9
Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem