Ullmann-Type Intramolecular C-O Reaction Toward Thieno[3,2-b]furan Derivatives with up to Six Fused Rings was written by Chen, Daoliang;Yuan, Dafei;Zhang, Cheng;Wu, Hao;Zhang, Jianyun;Li, Baolin;Zhu, Xiaozhang. And the article was included in Journal of Organic Chemistry in 2017.Safety of 2,3-Dibromobenzo[b]thiophene This article mentions the following:
In the presence of CuI and 1,10-phenanthroline, (fused) bromothienyl phenols such as I underwent intramol. Ullman coupling mediated by either K2CO3 or NaHCO3 in DMF to yield (fused) thienofurans such as II and III in 47-97% yields. The (fused) bromothienyl phenol reactants were prepared by regioselective Suzuki coupling of hydroxyphenylboronic acids with dibromothiophenes. The structures of II, III, and two dibenzothienofurans were determined by X-ray crystallog. The HOMO and LUMO energies were calculated for selected compounds, including III; the oxidation and reduction potentials of III were determined An organic field-effect transistor was prepared using III which exhibited p-type behavior. In the experiment, the researchers used many compounds, for example, 2,3-Dibromobenzo[b]thiophene (cas: 6287-82-7Safety of 2,3-Dibromobenzo[b]thiophene).
2,3-Dibromobenzo[b]thiophene (cas: 6287-82-7) belongs to benzothiophene derivatives. Functionalized benzothiophenes are important constructs found in molecules with wide ranging biological activity and in organic materials. Its aromaticity makes it relatively stable, although as a heterocycle, it has reactive sites which allow for functionalization.Safety of 2,3-Dibromobenzo[b]thiophene
Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem