New approach to the synthesis of 2-substituted benzothiophenes and their hetero analogs was written by Brown, Kenneth J.;Meth-Cohn, Otto. And the article was included in Tetrahedron Letters in 1974.HPLC of Formula: 55219-11-9 This article mentions the following:
Ozonolysis of thiophene gave 34% (o-OCHC6H4)2S2 (I) which with RCH2CO2H (R = CO2H, CN, Ph, 2-thienyl, 3-thienyl, BzNH, AcNH) gave 2-R-substituted benzothiophenes (II). Similarly, I with MeNO2 gave 2-nitrothiophene. I was also prepared by LiAlH4 reduction of (o-HO2CC6H4)2S2 followed by MnO2 oxidation Similarly the pyrazole III gave the thienopyrazole IV. In the experiment, the researchers used many compounds, for example, Benzo[b]thiophene-2-carbonitrile (cas: 55219-11-9HPLC of Formula: 55219-11-9).
Benzo[b]thiophene-2-carbonitrile (cas: 55219-11-9) belongs to benzothiophene derivatives. Benzothiophene finds use in research as a starting material for the synthesis of larger, usually bioactive structures. Its aromaticity makes it relatively stable, although as a heterocycle, it has reactive sites which allow for functionalization.HPLC of Formula: 55219-11-9
Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem