Mukherjee, Chandrani et al. published their research in Synlett in 2002 | CAS: 90560-10-4

6-Methoxybenzo[b]thiophene (cas: 90560-10-4) belongs to benzothiophene derivatives. Benzothiophene is relatively a stable molecule. The electrophilic substitution of benzothiophene systems is much less regioselective than that of indoles. It has been used as a raw material for the synthesis of biologically active structures and is found in pharmaceuticals such as leukotriene synthesis inhibitors and antifungals, as well as in many natural products.HPLC of Formula: 90560-10-4

Application of directed metalation in synthesis. Part 2. An expedient synthesis of methoxybenzo[b]thiophenes was written by Mukherjee, Chandrani;De, Asish. And the article was included in Synlett in 2002.HPLC of Formula: 90560-10-4 This article mentions the following:

A short, simple and expedient synthesis of substituted benzo[b]thiophenes involving directed ortho lithiation-side-chain deprotonation-cyclization-reduction is described. This method is a valuable improvement over earlier syntheses of the same class of compounds, both with respect to the number of steps and overall yields. In the experiment, the researchers used many compounds, for example, 6-Methoxybenzo[b]thiophene (cas: 90560-10-4HPLC of Formula: 90560-10-4).

6-Methoxybenzo[b]thiophene (cas: 90560-10-4) belongs to benzothiophene derivatives. Benzothiophene is relatively a stable molecule. The electrophilic substitution of benzothiophene systems is much less regioselective than that of indoles. It has been used as a raw material for the synthesis of biologically active structures and is found in pharmaceuticals such as leukotriene synthesis inhibitors and antifungals, as well as in many natural products.HPLC of Formula: 90560-10-4

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

 

Zhang, Yuan et al. published their research in Chemical Communications (Cambridge, United Kingdom) in 2020 | CAS: 10243-15-9

3-Bromo-2-methylbenzo[b]thiophene (cas: 10243-15-9) belongs to benzothiophene derivatives. Benzothiophene is a fused ring compound of thiophene ring and benzene ring, which is an important class of heterocycles with advantageous structures. It is found within the chemical structures of pharmaceutical drugs such as raloxifene, zileuton, and sertaconazole, and also BTCP.Product Details of 10243-15-9

Metal-directed synthesis of quadruple-stranded helical Eu(III) molecular switch: a significant improvement in photocyclization quantum yield was written by Zhang, Yuan;Zhou, Yanyan;Gao, Ting;Yan, Pengfei;Li, Hongfeng. And the article was included in Chemical Communications (Cambridge, United Kingdom) in 2020.Product Details of 10243-15-9 This article mentions the following:

The self-assembly of a quadruple-stranded Eu(III) helicate induces the conformation transformation of a DAE-based photochromic ligand from parallel to antiparallel, which brings a significant improvement in the photocyclization quantum yield (Φo-c) as compared with the free ligand. Furthermore, the photocontrolled open- and closed-rings of the ligand realized a reversible modulation toward Eu3+ center emission. In the experiment, the researchers used many compounds, for example, 3-Bromo-2-methylbenzo[b]thiophene (cas: 10243-15-9Product Details of 10243-15-9).

3-Bromo-2-methylbenzo[b]thiophene (cas: 10243-15-9) belongs to benzothiophene derivatives. Benzothiophene is a fused ring compound of thiophene ring and benzene ring, which is an important class of heterocycles with advantageous structures. It is found within the chemical structures of pharmaceutical drugs such as raloxifene, zileuton, and sertaconazole, and also BTCP.Product Details of 10243-15-9

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

 

Neckers, Douglas C. et al. published their research in Tetrahedron Letters in 1984 | CAS: 6287-82-7

2,3-Dibromobenzo[b]thiophene (cas: 6287-82-7) belongs to benzothiophene derivatives. Benzothiophene is relatively a stable molecule. The electrophilic substitution of benzothiophene systems is much less regioselective than that of indoles. It has been used as a raw material for the synthesis of biologically active structures and is found in pharmaceuticals such as leukotriene synthesis inhibitors and antifungals, as well as in many natural products.Recommanded Product: 2,3-Dibromobenzo[b]thiophene

Unimolecular heteroaromatic photoinitiators was written by Neckers, Douglas C.;Wagenaar, Frank L.. And the article was included in Tetrahedron Letters in 1984.Recommanded Product: 2,3-Dibromobenzo[b]thiophene This article mentions the following:

The synthesis and use for polymerization of new photoinitiators, I  [92613-07-5] and II  [92613-08-6] based on benzo[b]thiophene, is reported. The effectiveness of I and II for polymerization of Me methacrylate is compared to that of 2,3-dibromobenzo[b]thiophene  [6287-82-7]. In the experiment, the researchers used many compounds, for example, 2,3-Dibromobenzo[b]thiophene (cas: 6287-82-7Recommanded Product: 2,3-Dibromobenzo[b]thiophene).

2,3-Dibromobenzo[b]thiophene (cas: 6287-82-7) belongs to benzothiophene derivatives. Benzothiophene is relatively a stable molecule. The electrophilic substitution of benzothiophene systems is much less regioselective than that of indoles. It has been used as a raw material for the synthesis of biologically active structures and is found in pharmaceuticals such as leukotriene synthesis inhibitors and antifungals, as well as in many natural products.Recommanded Product: 2,3-Dibromobenzo[b]thiophene

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

 

Dienes, Yvonne et al. published their research in Chemistry – A European Journal in 2008 | CAS: 6287-82-7

2,3-Dibromobenzo[b]thiophene (cas: 6287-82-7) belongs to benzothiophene derivatives. Benzothiophene is relatively a stable molecule. The electrophilic substitution of benzothiophene systems is much less regioselective than that of indoles. It is found within the chemical structures of pharmaceutical drugs such as raloxifene, zileuton, sertaconazole, and also BTCP.Recommanded Product: 6287-82-7

Phosphorus-Based Heteropentacenes: Efficiently Tunable Materials for Organic n-Type Semiconductors was written by Dienes, Yvonne;Eggenstein, Matthias;Karpati, Tamas;Sutherland, Todd C.;Nyulaszi, Laszlo;Baumgartner, Thomas. And the article was included in Chemistry – A European Journal in 2008.Recommanded Product: 6287-82-7 This article mentions the following:

Benzo-condensed dithieno[3,2-b:2′,3′-d]phospholes were synthesized that allow convenient tuning of properties that are essential for application as semiconductor materials in organic field-effect transistor (OFET) devices. The versatile reactivity of the trivalent P atom in these heteropentacenes provides access to materials that show different photophys. properties, significantly different organization in the solid state, and distinctly different electrochem. properties that can be achieved by simple chem. modifications. The materials show strong photoluminescence in solution and in the solid state that depends on the electronic nature of the P center. Electrochem. studies revealed that the P atom intrinsically furnishes materials with n-channel or ambipolar behavior, also depending on its electronic nature. The exptl. data were verified by DFT quantum chem. calculations and suggest that the P-based heteropentacenes could be excellent candidates for n-channel OFET semiconductor materials. In the experiment, the researchers used many compounds, for example, 2,3-Dibromobenzo[b]thiophene (cas: 6287-82-7Recommanded Product: 6287-82-7).

2,3-Dibromobenzo[b]thiophene (cas: 6287-82-7) belongs to benzothiophene derivatives. Benzothiophene is relatively a stable molecule. The electrophilic substitution of benzothiophene systems is much less regioselective than that of indoles. It is found within the chemical structures of pharmaceutical drugs such as raloxifene, zileuton, sertaconazole, and also BTCP.Recommanded Product: 6287-82-7

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

 

Chatterjee, Anamitra et al. published their research in Angewandte Chemie, International Edition in 2019 | CAS: 6287-82-7

2,3-Dibromobenzo[b]thiophene (cas: 6287-82-7) belongs to benzothiophene derivatives. Benzothiophenes are valuable heterocycles that are widely used in medicines, agrochemicals, and materials science. The different substitution patterns in these heterocycles offer new opportunities for drug discovery and other applications in materials science.Formula: C8H4Br2S

Birch-Type Photoreduction of Arenes and Heteroarenes by Sensitized Electron Transfer was written by Chatterjee, Anamitra;Koenig, Burkhard. And the article was included in Angewandte Chemie, International Edition in 2019.Formula: C8H4Br2S This article mentions the following:

In the presence of Ir[dF(CF3)ppy]2(dtbbpy)(PF6), arenes such as anthracene underwent photochem. Birch reduction mediated by DIPEA and methylamine hydrochloride in DMF under 455 nm light to yield reduced arenes such as 9,10-dihydroanthracene using the accumulated energy of two photons per reduction Mechanistic investigations confirm that the combination of energy-transfer and electron-transfer processes generates an arene radical anion, which is subsequently trapped by hydrogen-atom transfer and finally protonated to form the dearomatized product. In the experiment, the researchers used many compounds, for example, 2,3-Dibromobenzo[b]thiophene (cas: 6287-82-7Formula: C8H4Br2S).

2,3-Dibromobenzo[b]thiophene (cas: 6287-82-7) belongs to benzothiophene derivatives. Benzothiophenes are valuable heterocycles that are widely used in medicines, agrochemicals, and materials science. The different substitution patterns in these heterocycles offer new opportunities for drug discovery and other applications in materials science.Formula: C8H4Br2S

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

 

Iddon, Brian et al. published their research in Journal of the Chemical Society in 1990 | CAS: 6287-82-7

2,3-Dibromobenzo[b]thiophene (cas: 6287-82-7) belongs to benzothiophene derivatives. Benzothiophenes are valuable heterocycles that are widely used in medicines, agrochemicals, and materials science. It is also used in the manufacturing of dyes such as thioindigo.Recommanded Product: 6287-82-7

Synthesis and reactions of 2,3,5,6-tetrahydro-2,5-ethano-3-benzazocin-4(1H)-one and a thieno-extended analog: x-ray structure of 3-methyl-2,3,5,6-tetrahydro-2,5-ethano[1]benzothieno[3,2-d]azocin-4(1H)-one was written by Iddon, Brian;Redhouse, Alan D.;Yat, Patrick N.. And the article was included in Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999) in 1990.Recommanded Product: 6287-82-7 This article mentions the following:

Hexahydromethanobenzocyclooctenone I (X = O) was prepared by condensation of o-xylene-α,α’-diyl dibromide with N-cyclopentylidenepyrrolidine and converted by Beckmann rearrangement of I (X = NOH) into tetrahydroethanobenzazocinone II (R = H). 2,3-Bis(bromomethyl)benzo[b]thiophene was converted similarly into a mixture of tetrahydroethanobenzothienoazocinones III (X1 = NH, X2 = CO; X1 = CO, X2 = NH). II (R = H) was N-methylated and II (R = H, Me) were reduced with LiAlH4 to the saturated products. Conversion of II (R = H) into the corresponding thiolactam with P2S5 followed by alkylation gave an N– or S-alkylated derivative, (e.g., IV, R = Me, Et), depending on the reagent and reaction conditions. The structures of a number of compounds in this work are based on the x-ray anal. of III (X1 = CO, X2 = NMe). In the experiment, the researchers used many compounds, for example, 2,3-Dibromobenzo[b]thiophene (cas: 6287-82-7Recommanded Product: 6287-82-7).

2,3-Dibromobenzo[b]thiophene (cas: 6287-82-7) belongs to benzothiophene derivatives. Benzothiophenes are valuable heterocycles that are widely used in medicines, agrochemicals, and materials science. It is also used in the manufacturing of dyes such as thioindigo.Recommanded Product: 6287-82-7

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

 

Floeistrup, Erik et al. published their research in Tetrahedron Letters in 2011 | CAS: 90560-10-4

6-Methoxybenzo[b]thiophene (cas: 90560-10-4) belongs to benzothiophene derivatives. Benzothiophene is relatively a stable molecule. The electrophilic substitution of benzothiophene systems is much less regioselective than that of indoles. It has been used as a raw material for the synthesis of biologically active structures and is found in pharmaceuticals such as leukotriene synthesis inhibitors and antifungals, as well as in many natural products.Reference of 90560-10-4

Synthesis of estradiol backbone mimics via the Stille reaction using copper(II) oxide as co-reagent was written by Floeistrup, Erik;Goede, Patrick;Stroemberg, Roger;Malm, Johan. And the article was included in Tetrahedron Letters in 2011.Reference of 90560-10-4 This article mentions the following:

Sterically hindered 2-phenylbenzo[b]thiophenes I (R1 = H, HO; R2 = H, Me; R3 = H, Me) and biaryls II (R4 = HO, PhCH2O; R5 = CHO) that can serve as templates for mimics of the estradiol backbone were prepared in modest to good yields by the Stille reaction using CuO as a coreagent. Due to the neutral conditions applied in the Stille reaction, protection strategies were unnecessary for hydroxy containing coupling partners. Ligandless coupling conditions were also evaluated. In the experiment, the researchers used many compounds, for example, 6-Methoxybenzo[b]thiophene (cas: 90560-10-4Reference of 90560-10-4).

6-Methoxybenzo[b]thiophene (cas: 90560-10-4) belongs to benzothiophene derivatives. Benzothiophene is relatively a stable molecule. The electrophilic substitution of benzothiophene systems is much less regioselective than that of indoles. It has been used as a raw material for the synthesis of biologically active structures and is found in pharmaceuticals such as leukotriene synthesis inhibitors and antifungals, as well as in many natural products.Reference of 90560-10-4

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

 

Quibell, Jacob M. et al. published their research in Chemical Science in 2018 | CAS: 6287-82-7

2,3-Dibromobenzo[b]thiophene (cas: 6287-82-7) belongs to benzothiophene derivatives. Benzothiophene finds use in research as a starting material for the synthesis of larger, usually bioactive structures. It is found within the chemical structures of pharmaceutical drugs such as zileuton, raloxifene, and sertaconazole, and also BTCP.Synthetic Route of C8H4Br2S

Transition-metal-free decarboxylative bromination of aromatic carboxylic acids was written by Quibell, Jacob M.;Perry, Gregory J. P.;Cannas, Diego M.;Larrosa, Igor. And the article was included in Chemical Science in 2018.Synthetic Route of C8H4Br2S This article mentions the following:

A transition metal-free decarboxylative bromination of aromatic acids was reported. The reaction is applicable to many electron-rich aromatic and heteroaromatic acids which have previously proved poor substrates for Hunsdiecker-type reactions. In addition, our preliminary mechanistic study suggested that radical intermediates are not involved in this reaction, which is in contrast to classical Hunsdiecker-type reactivity. Overall, the process demonstrates a useful method for producing valuable reagents from inexpensive and abundant starting materials. In the experiment, the researchers used many compounds, for example, 2,3-Dibromobenzo[b]thiophene (cas: 6287-82-7Synthetic Route of C8H4Br2S).

2,3-Dibromobenzo[b]thiophene (cas: 6287-82-7) belongs to benzothiophene derivatives. Benzothiophene finds use in research as a starting material for the synthesis of larger, usually bioactive structures. It is found within the chemical structures of pharmaceutical drugs such as zileuton, raloxifene, and sertaconazole, and also BTCP.Synthetic Route of C8H4Br2S

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

 

Gu, Lijun et al. published their research in Organic & Biomolecular Chemistry in 2016 | CAS: 55219-11-9

Benzo[b]thiophene-2-carbonitrile (cas: 55219-11-9) belongs to benzothiophene derivatives. Benzothiophenes are valuable heterocycles that are widely used in medicines, agrochemicals, and materials science. It is also used in the manufacturing of dyes such as thioindigo.HPLC of Formula: 55219-11-9

An aerobic Cu-mediated practical approach to aromatic nitriles using cyanide anions as the nitrogen source was written by Gu, Lijun;Jin, Cheng;Zhang, Hongtao;Liu, Jiyan;Li, Ganpeng;Yang, Zhi. And the article was included in Organic & Biomolecular Chemistry in 2016.HPLC of Formula: 55219-11-9 This article mentions the following:

A Cu-mediated cyanation of aryl Me ketones using cyanide anions as the nitrogen source was achieved to provide aromatic nitriles in moderate to good yields. The reaction tolerates a variety of synthetically important functional groups. In the experiment, the researchers used many compounds, for example, Benzo[b]thiophene-2-carbonitrile (cas: 55219-11-9HPLC of Formula: 55219-11-9).

Benzo[b]thiophene-2-carbonitrile (cas: 55219-11-9) belongs to benzothiophene derivatives. Benzothiophenes are valuable heterocycles that are widely used in medicines, agrochemicals, and materials science. It is also used in the manufacturing of dyes such as thioindigo.HPLC of Formula: 55219-11-9

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

 

Li, Lina et al. published their research in Bioorganic & Medicinal Chemistry in 2009 | CAS: 55219-11-9

Benzo[b]thiophene-2-carbonitrile (cas: 55219-11-9) belongs to benzothiophene derivatives. Benzothiophenes are valuable heterocycles that are widely used in medicines, agrochemicals, and materials science. The different substitution patterns in these heterocycles offer new opportunities for drug discovery and other applications in materials science.Recommanded Product: Benzo[b]thiophene-2-carbonitrile

Synthesis and evaluation of benzo[b]thiophene derivatives as inhibitors of alkaline phosphatases was written by Li, Lina;Chang, Lei;Pellet-Rostaing, Stephane;Liger, Francois;Lemaire, Marc;Buchet, Rene;Wu, Yuqing. And the article was included in Bioorganic & Medicinal Chemistry in 2009.Recommanded Product: Benzo[b]thiophene-2-carbonitrile This article mentions the following:

Presence of basic calcium phosphate in knee joints of osteoarthritis patients could be prevented by inhibiting tissue non-specific alk. phosphatase (TNAP) activity. Levamisole or the L stereoisomer of tetramisole (a known TNAP inhibitor) has been used as a treatment for curing rheumatoid arthritis but its therapeutical use is limited due to side effects. We report the synthesis and the TNAP inhibition property of benzo[b]thiophene derivatives, among which benzothiopheno-tetramisole and benzothiopheno-2,3-dehydrotetramisole, which could be involved in a drug therapy for osteoarthritis. Two water soluble racemic benzothiopheno-tetramisole and -2,3-dehydrotetramisole with apparent inhibition constants K i = 85 ± 6 μM and 135 ± 3 μM (n = 3) comparable to that of enantiomeric levamisole 93 ± 4 μM were found. Several novel derivatives showed more pronounced inhibition properties towards intestinal alk. phosphatase than TNAP. In the experiment, the researchers used many compounds, for example, Benzo[b]thiophene-2-carbonitrile (cas: 55219-11-9Recommanded Product: Benzo[b]thiophene-2-carbonitrile).

Benzo[b]thiophene-2-carbonitrile (cas: 55219-11-9) belongs to benzothiophene derivatives. Benzothiophenes are valuable heterocycles that are widely used in medicines, agrochemicals, and materials science. The different substitution patterns in these heterocycles offer new opportunities for drug discovery and other applications in materials science.Recommanded Product: Benzo[b]thiophene-2-carbonitrile

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem