One-pot conversion of aromatic bromides and aromatics into aromatic nitriles was written by Ushijima, Sousuke;Togo, Hideo. And the article was included in Synlett in 2010.Related Products of 55219-11-9 This article mentions the following:
Various aromatic bromides and iodides were smoothly converted into the corresponding aromatic nitriles in good to moderate yields by sequential treatment with BuLi and DMF, followed by treatment with I2 in aqueous NH3. The same treatment of typical aromatics and heteroaromatics also provided the corresponding aromatic nitriles in good yields. The present reactions are novel 1-pot methods for the preparation of aromatic nitriles from aromatic bromides and aromatics, resp., through the formation of aryllithiums and their DMF adducts. In the experiment, the researchers used many compounds, for example, Benzo[b]thiophene-2-carbonitrile (cas: 55219-11-9Related Products of 55219-11-9).
Benzo[b]thiophene-2-carbonitrile (cas: 55219-11-9) belongs to benzothiophene derivatives. Benzothiophene scaffolds are of great importance due to its increased presence in bioactive molecules. Its aromaticity makes it relatively stable, although as a heterocycle, it has reactive sites which allow for functionalization.Related Products of 55219-11-9
Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem