Certain applications of heteroatom directed ortho-metalation in sulfur heterocycles was written by Pradhan, Tarun Kanti;Ghosh, Sukhen Chandra;De, Asish. And the article was included in ARKIVOC (Gainesville, FL, United States) in 2003.SDS of cas: 90560-10-4 This article mentions the following:
Substituted benzothiophenes are prepared via heteroatom directed ortho-metalation of di-Et arylamides to introduce a methylsulfanyl group which upon deprotonation underwent intramol. cyclization to form intermediate thioindoxyls that are reduced with sodium borohydride to the corresponding benzothiophene derivative Addnl., heteroatom directed ortho-metalation of benzothiophenes is demonstrated to prepare benzothiophene analogs and heterocyclic analogs. This data is accompanied by a review of work from the author’s laboratory regarding application of directed ortho-metalation in sulfur heterocycles. In the experiment, the researchers used many compounds, for example, 6-Methoxybenzo[b]thiophene (cas: 90560-10-4SDS of cas: 90560-10-4).
6-Methoxybenzo[b]thiophene (cas: 90560-10-4) belongs to benzothiophene derivatives. Benzothiophene is relatively a stable molecule. The electrophilic substitution of benzothiophene systems is much less regioselective than that of indoles. Its aromaticity makes it relatively stable, although as a heterocycle, it has reactive sites which allow for functionalization.SDS of cas: 90560-10-4
Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem