Synthesis of 6-thiaellipticine and related compounds via heterocyclic o-quinodimethane intermediates was written by Kano, Shinzo;Mochizuki, Naoki;Hibino, Satoshi;Shibuya, Shiroshi. And the article was included in Journal of Organic Chemistry in 1982.Recommanded Product: 10243-15-9 This article mentions the following:
Pyrolysis of tertiary alcs. I (R = 2-pyridyl, R1 = Me,Et) at 400 °C for 7 min gave benzo[b]thieno[3,2-g]quinolines II (R2 = H, Me) and benzo[b]thieno[2,3-g]isoquinolines III (R2 = H, Me) through cyclization of the corresponding benzo[b]thiophene-2,3-quinodimethane intermediates. Pyrolysis of I (R = 3-pyridyl, R1 = Me,Et) afforded benzo[b]thieno[3,2-g]isoquinolines IV (R2 = H, Me). Pyrolysis of V gave 5-methyl-benzo[b]thieno[2,3-g]isoquinoline and III (R2 = H, Me). The alcs. VI (R3R4 = CH:CHCH:CH, X = O, S; R3 = R4 = H, X = S; R3R4 CH:NCH:CH, X = S) underwent similar cyclizations. In the experiment, the researchers used many compounds, for example, 3-Bromo-2-methylbenzo[b]thiophene (cas: 10243-15-9Recommanded Product: 10243-15-9).
3-Bromo-2-methylbenzo[b]thiophene (cas: 10243-15-9) belongs to benzothiophene derivatives. Benzothiophene is used as starting material for the synthesis of bioactive molecules. The core structure is a part of various pharmaceutical substances and natural products. The different substitution patterns in these heterocycles offer new opportunities for drug discovery and other applications in materials science.Recommanded Product: 10243-15-9
Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem