Reductive dehalogenation with sodium hydrazide and hydrazine was written by Kauffmann, Th.;Henkler, H.;Zengel, H.. And the article was included in Angewandte Chemie in 1962.Product Details of 6287-82-7 This article mentions the following:
Aromatic halides react rapidly in benzene or Et2O solution with excess NaNHNH2 and H2NNH2 (halide, reaction temperature, product, and % yield given): mesityl bromide, 25°, mesitylene, 82; o-(m-, p-)bromoanisole, 20°, anisole, 58 (30, 38); 1(2)-bromonaphthalene, 0°, naphthalene, 75 (52); 1(2)-chloronaphthalene, 0°, naphthalene, 65 (75); 1(2)-fluoronaphthalene, 25° (0°), naphthalene, 39 (60); 9-bromoanthracene, 0°, anthracene, 90; 2,3-dibromocumarone, 0°, cumarone, 85; 2,3-dibromothionaphthene, 45°, thionaphthene, 74; 4-bromoisoquinoline, 0°, isoquinoline, 57; 1-chloroferrocene, 30°, ferrocene, 97. In the experiment, the researchers used many compounds, for example, 2,3-Dibromobenzo[b]thiophene (cas: 6287-82-7Product Details of 6287-82-7).
2,3-Dibromobenzo[b]thiophene (cas: 6287-82-7) belongs to benzothiophene derivatives. Benzothiophenes are valuable heterocycles that are widely used in medicines, agrochemicals, and materials science. It is found within the chemical structures of pharmaceutical drugs such as raloxifene, zileuton, and sertaconazole, and also BTCP.Product Details of 6287-82-7
Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem