Substitution reactions of benzo[b]thiophen derivatives. I. Bromination and nitration of 2,3-dibromobenzo[b]thiophen and its 5-methyl derivative was written by Cooper, J.;Ewing, D. F.;Scrowston, R. M.;Westwood, R.. And the article was included in Journal of the Chemical Society [Section] C: Organic in 1970.Reference of 6287-82-7 This article mentions the following:
Bromination of 2,3-dibromobenzo[b]thiophene in CHCl3 or AcOH gives the 2,3,6-tribromo derivative; nitration gives a mixture of 2,3,6-tribromo- (25%), 2,3,4-tribromo- (3%), 2,3-dibromo-6-nitro- (32%), and 2,3-dibromo-4-nitrobenzo[b]thiophene (36%). Analogous results are obtained for the bromination and nitration of 2,3-dibromo-5-methylbenzo[b]thiophene, except that the presence of the 5-methyl group increases the proportion of the 4-substituted product in each case. The structures assigned are supported by a detailed anal. of their 1H NMR spectra. In the experiment, the researchers used many compounds, for example, 2,3-Dibromobenzo[b]thiophene (cas: 6287-82-7Reference of 6287-82-7).
2,3-Dibromobenzo[b]thiophene (cas: 6287-82-7) belongs to benzothiophene derivatives. Benzothiophene is relatively a stable molecule. The core structure is a part of various pharmaceutical substances and natural products. It is also used in the manufacturing of dyes such as thioindigo.Reference of 6287-82-7
Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem