Iridium-Catalyzed Hydrogen Transfer: Synthesis of Substituted Benzofurans, Benzothiophenes, and Indoles from Benzyl Alcohols was written by Anxionnat, Bruno;Gomez Pardo, Domingo;Ricci, Gino;Rossen, Kai;Cossy, Janine. And the article was included in Organic Letters in 2013.Category: benzothiophene This article mentions the following:
An iridium-catalyzed hydrogen transfer has been developed in the presence of p-benzoquinone, allowing the synthesis of a diversity of substituted benzofurans, benzothiophenes, and indoles from substituted benzylic alcs. E.g., in presence of [IrCp*Cl2]2, p-benzoquinone, and Cs2CO3, hydrogen transfer/cyclization of benzylic alc. (I) gave 98% benzofuran derivative (II). In the experiment, the researchers used many compounds, for example, Benzo[b]thiophene-2-carbonitrile (cas: 55219-11-9Category: benzothiophene).
Benzo[b]thiophene-2-carbonitrile (cas: 55219-11-9) belongs to benzothiophene derivatives. Benzothiophene scaffolds are of great importance due to its increased presence in bioactive molecules. It is found within the chemical structures of pharmaceutical drugs such as raloxifene, zileuton, and sertaconazole, and also BTCP.Category: benzothiophene
Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem