Synthesis of nitriles via the iodine-mediated dehydrosulfurization of thioamides was written by Murata, Yuki;Iwasa, Hitomi;Matsumura, Mio;Yasuike, Shuji. And the article was included in Chemical & Pharmaceutical Bulletin in 2020.SDS of cas: 55219-11-9 This article mentions the following:
A simple general method for the synthesis of nitriles using the inexpensive and easy to handle iodine (I2) is described herein. The reaction of thioamides with I2 in the presence of triethylamine at room temperature under aerobic conditions afforded various nitriles bearing aryl, vinyl, and alkyl groups in good-to-excellent yields. This method was also effective for conversion of thioureas to cyanamides. In the experiment, the researchers used many compounds, for example, Benzo[b]thiophene-2-carbonitrile (cas: 55219-11-9SDS of cas: 55219-11-9).
Benzo[b]thiophene-2-carbonitrile (cas: 55219-11-9) belongs to benzothiophene derivatives. Functionalized benzothiophenes are important constructs found in molecules with wide ranging biological activity and in organic materials. It is found within the chemical structures of pharmaceutical drugs such as zileuton, raloxifene, and sertaconazole, and also BTCP.SDS of cas: 55219-11-9
Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem