Large-scale preparation of aromatic fluorides via electrophilic fluorination with functionalized aryl- or heteroarylmagnesium reagents was written by Yamada, Shigeyuki;Knochel, Paul. And the article was included in Synthesis in 2010.Quality Control of 3-Bromo-2-methylbenzo[b]thiophene This article mentions the following:
Functionalized aryl- or heteroarylmagnesium reagents, prepared from the corresponding bromides or iodides using halogen-Mg exchange or direct Mg insertion in the presence of LiCl, reacted smoothly with (PhSO2)2NF in mixed solvent (4:1 CH2Cl2-perfluorodecalin) to give the corresponding aromatic fluorides in moderate to good yields. In the experiment, the researchers used many compounds, for example, 3-Bromo-2-methylbenzo[b]thiophene (cas: 10243-15-9Quality Control of 3-Bromo-2-methylbenzo[b]thiophene).
3-Bromo-2-methylbenzo[b]thiophene (cas: 10243-15-9) belongs to benzothiophene derivatives. Benzothiophene finds use in research as a starting material for the synthesis of larger, usually bioactive structures. It is also used in the manufacturing of dyes such as thioindigo.Quality Control of 3-Bromo-2-methylbenzo[b]thiophene
Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem