Isoxazolines by cycloadditions of mesitonitrile oxide with benzo[b]thiophene S-oxide and S,S-dioxide. Structural studies, theoretical explanations, and kinetics was written by Bened, Armand;Durand, Robert;Pioch, Daniel;Geneste, Patrick;Declercq, Jean Paul;Germain, Gabriel;Rambaud, Joelle;Roques, Raymond;Guimon, Claude;Pfister Guillouzo, Genevieve. And the article was included in Journal of Organic Chemistry in 1982.COA of Formula: C8H4Br2S This article mentions the following:
1,3-Dipolar cycloadditions were examined for 2,4,6-Me3C6H2CNO with benzo[b]thiophene S-oxide and S,S-dioxide derivatives having a Me, piperidino, Cl or Br substituent on the active thiophene double bond. These dipolarophiles are more reactive than the original S compound The S-oxide and S,S-dioxide derivatives show nearly the same ability to form adducts. Between the 2 possible regioisomers, only the 2,3-dihydrobenzo[b]thieno[2,3-d]isoxazolines (e.g., I) are formed. The regioselectivity is discussed in terms of frontier MO interactions on the basis of the photoelectron spectra and CNDO/S calculations There is no stereoselectivity with the S-oxides, and both syn and anti adducts are obtained. The Cl and Br derivatives do not form adducts. In the experiment, the researchers used many compounds, for example, 2,3-Dibromobenzo[b]thiophene (cas: 6287-82-7COA of Formula: C8H4Br2S).
2,3-Dibromobenzo[b]thiophene (cas: 6287-82-7) belongs to benzothiophene derivatives. Benzothiophenes are valuable heterocycles that are widely used in medicines, agrochemicals, and materials science. The different substitution patterns in these heterocycles offer new opportunities for drug discovery and other applications in materials science.COA of Formula: C8H4Br2S
Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem