Fischer Dinuclear and Mononuclear Bis-Carbene Complexes of Thiophene and Thiophene Derivatives was written by Lotz, Simon;van Jaarsveld, Nina A.;Liles, David C.;Crause, Chantelle;Gorls, Helmar;Terblans, Yvette M.. And the article was included in Organometallics in 2012.Product Details of 6287-82-7 This article mentions the following:
The reaction of dilithiated thiophene and thiophene derivatives with group 6 transition metal carbonyl precursors and subsequent alkylation afforded linearly arranged Fischer 2,5-bis-carbene and the rare unsym. 2,3-bis-carbene chelated complexes. The latter requires a second lithiation to occur at an adjacent, less reactive site on the thiophene ring. The control of reactivity sites was investigated and achieved by either blocking more reactive positions with substituents or activating less reactive positions by lithium-halogen exchange reactions. A series of Fischer bis-carbene chelates were synthesized by manipulating the above variables. Structural features of Fischer mono-carbene, mononuclear bis-carbene, and bis-carbene chelated complexes were studied by IR, NMR, and single-crystal x-ray diffraction. In the experiment, the researchers used many compounds, for example, 2,3-Dibromobenzo[b]thiophene (cas: 6287-82-7Product Details of 6287-82-7).
2,3-Dibromobenzo[b]thiophene (cas: 6287-82-7) belongs to benzothiophene derivatives. Benzothiophene is relatively a stable molecule. The electrophilic substitution of benzothiophene systems is much less regioselective than that of indoles. It has been used as a raw material for the synthesis of biologically active structures and is found in pharmaceuticals such as leukotriene synthesis inhibitors and antifungals, as well as in many natural products.Product Details of 6287-82-7
Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem