Dickinson, R. P. et al. published their research in Tetrahedron Letters in 1970 | CAS: 10243-15-9

3-Bromo-2-methylbenzo[b]thiophene (cas: 10243-15-9) belongs to benzothiophene derivatives. Benzothiophene is relatively a stable molecule. The electrophilic substitution of benzothiophene systems is much less regioselective than that of indoles. It has been used as a raw material for the synthesis of biologically active structures and is found in pharmaceuticals such as leukotriene synthesis inhibitors and antifungals, as well as in many natural products.HPLC of Formula: 10243-15-9

Stability of 3-benzo[b]thienyl-lithium was written by Dickinson, R. P.;Iddon, B.. And the article was included in Tetrahedron Letters in 1970.HPLC of Formula: 10243-15-9 This article mentions the following:

Title compound (I) prepared from 3-bromobenzo[b]thiophene and BuLi was unstable in Et2O above – 70° and at 20° in the presence of Me2SO4 gave o-MeSC6H4CCH, o-MeSC6H4CCMe, benzo[b]thiophene, and 3-bromo-2-methylbenzo[b]thiophene. After 18 hr at 20° o-BuSC6H4CCMe was also obtained. Treatment of I with CO2 after 30 min at 20° gave benzo[b]thiophene-2-carboxylic acid and its 3-bromo derivative In the experiment, the researchers used many compounds, for example, 3-Bromo-2-methylbenzo[b]thiophene (cas: 10243-15-9HPLC of Formula: 10243-15-9).

3-Bromo-2-methylbenzo[b]thiophene (cas: 10243-15-9) belongs to benzothiophene derivatives. Benzothiophene is relatively a stable molecule. The electrophilic substitution of benzothiophene systems is much less regioselective than that of indoles. It has been used as a raw material for the synthesis of biologically active structures and is found in pharmaceuticals such as leukotriene synthesis inhibitors and antifungals, as well as in many natural products.HPLC of Formula: 10243-15-9

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem