Rhodium-catalyzed cycloisomerization of ester-tethered 1,6-diynes with cyclopropanol moiety leading to tetralone/exocyclic diene hybrid molecules was written by Yasui, Takeshi;Kikuchi, Tomohiro;Yamamoto, Yoshihiko. And the article was included in Chemical Communications (Cambridge, United Kingdom) in 2020.Application In Synthesis of 2,5-Dimethylthiophene The following contents are mentioned in the article:
The rhodium-catalyzed cycloisomerization of ester-tethered 1,6-diynes bearing a cyclopropanol moiety produced tetralone/exocyclic diene hybrid mols. with thermodynamically unfavorable alkene geometry. The results of control experiments and d. functional theory calculations suggest that the ester tether plays an important role in the efficiency of E/Z isomerization processes. This study involved multiple reactions and reactants, such as 2,5-Dimethylthiophene (cas: 638-02-8Application In Synthesis of 2,5-Dimethylthiophene).
2,5-Dimethylthiophene (cas: 638-02-8) belongs to benzothiophene derivatives. Functionalized benzothiophenes are important constructs found in molecules with wide ranging biological activity and in organic materials. Its aromaticity makes it relatively stable, although as a heterocycle, it has reactive sites which allow for functionalization.Application In Synthesis of 2,5-Dimethylthiophene
Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem