Watson, Nathanial E. et al. published their research in Analytical Chemistry (Washington, DC, United States) in 2017 | CAS: 638-02-8

2,5-Dimethylthiophene (cas: 638-02-8) belongs to benzothiophene derivatives. Benzothiophene scaffolds are of great importance due to its increased presence in bioactive molecules. Its aromaticity makes it relatively stable, although as a heterocycle, it has reactive sites which allow for functionalization.COA of Formula: C6H8S

Comprehensive Three-Dimensional Gas Chromatography with Time-of-Flight Mass Spectrometry was written by Watson, Nathanial E.;Bahaghighat, H. Daniel;Cui, Ke;Synovec, Robert E.. And the article was included in Analytical Chemistry (Washington, DC, United States) in 2017.COA of Formula: C6H8S The following contents are mentioned in the article:

Development of comprehensive, three-dimensional (3D) gas chromatog. with time-of-flight mass spectrometric detection (GC3/TOFMS) is described. This instrument provides four dimensions (4D) of chem. selectivity and includes significant improvements to total selectivity (mass spectrometric and chromatog.), peak identification, and operational temperature range relative to previous models of the GC3 reported. The new instrumental design and data output are evaluated and illustrated via two samples, a 115-component test mixture and a diesel fuel spiked with several compounds, for the purpose of illustrating the chem. selectivity benefits of this instrumental platform. Useful approaches to visualize the 4-dimensional data are presented. The GC3/TOFMS instrument exptl. achieved total peak capacity, nc,3D, ranging from 5000 to 9600 (x̅ = 7000, s = 1700) for 10 representative analytes for 50 min separations with component dimensional peak capacities averaging 406, 3.6, and 4.9 for 1D, 2D, and 3D, resp. Particularly, GC3/TOFMS achieved a combined 2D × 3D peak capacity ranging from 10 to 26 (x̅ = 17.6, s = 5.0), which is similar to what is achieved by 2D alone in a GC × GC operating at equivalent modulation period conditions. The anal. benefits of employing three varied chem. selectivities in the 3-dimensional separation coupled with TOFMS are illustrated through the separation and detection of 1,6-dichlorohexane and cyclohexyl isothiocyanate as part of the diesel fuel anal. This study involved multiple reactions and reactants, such as 2,5-Dimethylthiophene (cas: 638-02-8COA of Formula: C6H8S).

2,5-Dimethylthiophene (cas: 638-02-8) belongs to benzothiophene derivatives. Benzothiophene scaffolds are of great importance due to its increased presence in bioactive molecules. Its aromaticity makes it relatively stable, although as a heterocycle, it has reactive sites which allow for functionalization.COA of Formula: C6H8S

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem