Reactions of a 3-phenyl-1-trifluoromethyl-prop-2-yne iminium salt with furans, thiophenes, and pyrroles was written by Schneider, Thomas;Heinrich, Georg;Koch, Raphael;Maas, Gerhard. And the article was included in European Journal of Organic Chemistry in 2021.Recommanded Product: 638-02-8 The following contents are mentioned in the article:
Reactions of a novel propyne iminium salt, N,N-di-Me 3-phenyl-1-trifluoromethyl-propyne iminium triflate, with electron-rich heteroaromatic ring systems (furans, thiophenes, pyrroles) are reported. The 1-CF3-propyne iminium ion can act as a highly reactive ambident electrophile, giving rise to simple electrophilic heteroaromatic ring substitution products, and as a 1,3-biselectrophile leading to C2+C3-CF3 annulation products. Moreover, it is an electron-deficient alkyne which was found to afford double [2+2] cycloaddition products with 2,5-dimethylfuran and 2,5-dimethylthiophene. The obtained mol. structures include CF3-containing compounds with cyclopenta[b]furan, cyclopenta[b]thiophene, cyclopenta[c]thiophene, cyclopenta[b]pyrrole, cyclopenta[c]pyrrole, 3H-pyrrolizine, and 1,4-dihydrocyclopenta[b]pyrrole ring systems. Analogous reactions of 1,3(or 1,4)-phenylenebis(1-CF3-propyne iminium) salts with furans, pyrroles or thiophenes in a 2 : 1 stoichiometry lead to phenylene-tethered condensed heterocycles of the same type. This study involved multiple reactions and reactants, such as 2,5-Dimethylthiophene (cas: 638-02-8Recommanded Product: 638-02-8).
2,5-Dimethylthiophene (cas: 638-02-8) belongs to benzothiophene derivatives. Benzothiophene is a fused ring compound of thiophene ring and benzene ring, which is an important class of heterocycles with advantageous structures. It is also used in the manufacturing of dyes such as thioindigo.Recommanded Product: 638-02-8
Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem