In-vitro evaluation of the antioxidant and anti-inflammatory activity of volatile compounds and minerals in five different onion varieties was written by Sami, Rokayya;Elhakem, Abeer;Alharbi, Mona;Almatrafi, Manal;Benajiba, Nada;Mohamed, Taha Ahmed;Fikry, Mohammad;Helal, Mahmoud. And the article was included in Separations in 2021.Formula: C6H8S The following contents are mentioned in the article:
Onions contain high antioxidants compounds that fight inflammation against many diseases. The purpose was to investigate some selected bioactive activities of onion varieties (Yellow, Red, Green, Leek, and Baby). Antioxidant assays and anti-inflammatory activities such as NO production with the addition of some bioactive components were determined and analyzed by using a spectrophotometer. Gas chromatog. and mass spectrometry (GC-MS) was used for the volatile compounds, while an Atomic absorption spectrometer was used for mineral determinations Red variety achieved the highest antioxidant activities. The total flavonoids were between (12.56 and 353.53 mg Quercetin/gin dry weight) (dw) and the total phenol was (8.75-25.73 mg/g dw). Leek, Yellow and Green extracts achieved highly anti-inflammatory values (3.71-4.01 μg/mL) followed by Red and Baby extracts, resp. The highest contents of sodium, potassium, zinc, and calcium were established for Red onions. Furfuraldehyde, 5-Methyl-2-furfuraldehyde, 2-Methyl-2-pentenal, and 1-Propanethiol were the most predominant, followed by a minor abundance of the other compounds such as Di-Me sulfide, Me allyl disulfide, Methyl-trans-propenyl-disulfide, and Me Pr disulfide. The results recommend that these varieties could act as sources of essential antioxidants and anti-inflammatories to decrease inflammation and oxidative stresses, especially red onions that recorded high activities. This study involved multiple reactions and reactants, such as 2,5-Dimethylthiophene (cas: 638-02-8Formula: C6H8S).
2,5-Dimethylthiophene (cas: 638-02-8) belongs to benzothiophene derivatives. Benzothiophene is relatively a stable molecule. The electrophilic substitution of benzothiophene systems is much less regioselective than that of indoles. Due to its aromaticity, thiophenes do not exhibit the same properties as conventional thioethers.Formula: C6H8S
Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem