Efficient Hydrogenation of Biomass Oxoacids to Lactones by Using NHC-Iridium Coordination Polymers as Solid Molecular Catalysts was written by Liu, Yaoqi;Sun, Zheming;Huang, Changyu;Tu, Tao. And the article was included in Chemistry – An Asian Journal in 2017.Application In Synthesis of 2,5-Dimethylthiophene The following contents are mentioned in the article:
A series of NHC-iridium coordination polymers have proven to be robust, efficient and recyclable solid mol. catalysts toward the hydrogenation of biomass levulinic acid (LA) to γ-valerolactone. Along with quant. yields attained at 0.01 mol % catalyst loading under 50 atm of H2, the solid mol. catalyst was readily recovered and reused for 12 runs without obvious loss of the selectivity and activity. Remarkably, up to 1.2×105 TON, an unprecedented value could be achieved in this important transformation. In addition, a number of LA homologues, analogs and derivatives were well tolerated to deliver various intriguing and functional lactones in good to excellent yields, which further confirmed the feasibility of the solid mol. catalysts. This study involved multiple reactions and reactants, such as 2,5-Dimethylthiophene (cas: 638-02-8Application In Synthesis of 2,5-Dimethylthiophene).
2,5-Dimethylthiophene (cas: 638-02-8) belongs to benzothiophene derivatives. Functionalized benzothiophenes are important constructs found in molecules with wide ranging biological activity and in organic materials. It is found within the chemical structures of pharmaceutical drugs such as raloxifene, zileuton, sertaconazole, and also BTCP.Application In Synthesis of 2,5-Dimethylthiophene
Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem