In vitro antischistosomal activity of Allium cepa L. (red onion) extracts and identification of the essential oil composition by GC-MS was written by Abdel-Lateef, Ezzat;Rabia, Ibrahim;Abdel-Gawad, Mahfouz;El-Sayed, Mortada. And the article was included in Journal of Microbiology, Biotechnology and Food Sciences in 2018.Category: benzothiophene The following contents are mentioned in the article:
Allium cepa L. (red onion) is one of the most famous vegetable crops grown in Egypt due to its medical and nutritional importance. In vitro antischistosomal bioassay of Et acetate (EtOAc) and butanolic (BuOH) fractions derived from methanolic (MeOH) extract of A. cepa as well as the essential oil of plant bulbs was carried out using ascending doses. The chem. constituents of essential oil were further investigated using GC-MS anal. The results revealed that the MeOH extract, EtOAc fraction, BuOH fraction and essential oil have a significant effect on adult Schistosoma mansoni worms. The essential oil of A. cepa gave high worm mortality (%) at the concentration 500 μg/mL (75%), 250 g/mL (50%) and 125 μg/mL (30%) death rate after 24 h. GC-MS anal. of A. cepa essential oil exhibited different chem. volatile constituents such as organosulfur compounds, alcs., acids, esters, furans, phenols, and aldehyde. 3, 5-Diethyl -1, 2, 4-trithiolane (10.17%), 1, 3, 5-trithiolane (7.80%), and 3-(2H-furanone, 2-hexyl-5-methyl) (7.74%) represented the highest contents percent in essential oil of A. cepa bulbs. In conclusion, the bulbs of A. cepa exhibited antischistosomal activities and contain a variety of bioactive chem. constituents and can be considered as a natural antischistosomal agent. This study involved multiple reactions and reactants, such as 2,5-Dimethylthiophene (cas: 638-02-8Category: benzothiophene).
2,5-Dimethylthiophene (cas: 638-02-8) belongs to benzothiophene derivatives. Functionalized benzothiophenes are important constructs found in molecules with wide ranging biological activity and in organic materials. It is found within the chemical structures of pharmaceutical drugs such as raloxifene, zileuton, sertaconazole, and also BTCP.Category: benzothiophene
Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem