Day: November 21, 2022

Cui, Dong published the artcileNear-infrared absorbing amphiphilic semiconducting polymers for photoacoustic imaging, Product Details of C21H26Br4S2, the publication is Journal of Materials Chemistry B: Materials for Biology and Medicine (2017), 5(23), 4406-4409, database is CAplus and MEDLINE.

Development of photoacoustic (PA) imaging agents is crucial to advancing PA imaging in biol. and medicine. In this study, we report the design and synthesis of near-IR (NIR) absorbing amphiphilic semiconducting polymers that can spontaneously self-assemble into homogeneous water-soluble nanoparticles for PA imaging of tumor in living mice.

Journal of Materials Chemistry B: Materials for Biology and Medicine published new progress about 1426829-76-6. 1426829-76-6 belongs to benzothiophene, auxiliary class Other Aromatic Heterocyclic,Bromide, name is 2,6-Dibromo-4,4-bis(6-bromohexyl)-4H-cyclopenta[1,2-b:5,4-b’]dithiophene, and the molecular formula is C21H26Br4S2, Product Details of C21H26Br4S2.

Referemce:
https://en.wikipedia.org/wiki/Benzothiophene,
Benzothiophene | C8H6S – PubChem

Pang, Shuting published the artcileA Facile Synthesized Polymer Featuring B-N Covalent Bond and Small Singlet-Triplet Gap for High-Performance Organic Solar Cells, COA of Formula: C34H40F2S4, the publication is Angewandte Chemie, International Edition (2021), 60(16), 8813-8817, database is CAplus and MEDLINE.

High-efficiency organic solar cells (OSCs) largely rely on polymer donors. Herein, we report a new building block BNT and a relevant polymer PBNT-BDD featuring B-N covalent bond for application in OSCs. The BNT unit was synthesized in only 3 steps, leading to the facile synthesis of PBNT-BDD. When blended with a nonfullerene acceptor Y6-BO, PBNT-BDD afforded a power conversion efficiency (PCE) of 16.1% in an OSC, comparable to the benzo[1,2-b:4,5-b’]dithiophene (BDT)-based counterpart. The nonradiative recombination energy loss of 0.19 eV was afforded by PBNT-BDD. PBNT-BDD also exhibited weak crystallinity and appropriate miscibility with Y6-BO, benefitting of morphol. stability. The singlet-triplet gap (ΔE_ST) of PBNT-BDD is as low as 0.15 eV, which is much lower than those of common organic semiconductors (≥0.6 eV). As a result, the triplet state of PBNT-BDD is higher than the charge transfer (CT) state, which would suppress the recombination via triplet state effectively.

Angewandte Chemie, International Edition published new progress about 1514905-24-8. 1514905-24-8 belongs to benzothiophene, auxiliary class Organic Photo-Voltaic Materials, OPV,BDT Donors, name is 4,8-Bis(5-(2-ethylhexyl)-4-fluorothiophen-2-yl)benzo[1,2-b:4,5-b’]dithiophene, and the molecular formula is C34H40F2S4, COA of Formula: C34H40F2S4.

Referemce:
https://en.wikipedia.org/wiki/Benzothiophene,
Benzothiophene | C8H6S – PubChem

Li, Zhao published the artcileCombined Dynamic Kinetic Resolution and C-H Functionalization for Facile Synthesis of Non-Biaryl-Atropisomer-Type Axially Chiral Organosilanes, Application of (1-Benzothiophen-4-yl)boronic acid, the publication is Chemistry – A European Journal (2021), 27(13), 4336-4340, database is CAplus and MEDLINE.

Although asym. C-H functionalization was available for the synthesis of structurally diverse mols., catalytic dynamic kinetic resolution (DKR) approaches to change racemic stereogenic axes remain synthetic challenges in this field. Here, a concise Pd-catalyzed DKR was combined with C-H functionalization involving olefination and alkynylation for the highly efficient synthesis of nonbiaryl-atropisomer-type (NBA) axially chiral organosilanes. The chem. proceeded through two different and distinct DKR: 1st, an atroposelective C-H olefination or alkynylation produced axially chiral vinylsilanes or alkynylsilanes as a new family of nonbiaryl atropisomers (NBA), and 2nd, the extension of this DKR strategy to 2-fold o,o’-C-H functionalization led to the multifunctional axially chiral organosilicon compounds with up to >99% ee.

Chemistry – A European Journal published new progress about 177735-30-7. 177735-30-7 belongs to benzothiophene, auxiliary class Boronic acid and ester,Benzothiophene,Boronic Acids,Boronic acid and ester, name is (1-Benzothiophen-4-yl)boronic acid, and the molecular formula is C8H7BO2S, Application of (1-Benzothiophen-4-yl)boronic acid.

Referemce:
https://en.wikipedia.org/wiki/Benzothiophene,
Benzothiophene | C8H6S – PubChem

Zhang, Shaoqing published the artcileOver 14% Efficiency in Polymer Solar Cells Enabled by a Chlorinated Polymer Donor, SDS of cas: 1514905-24-8, the publication is Advanced Materials (Weinheim, Germany) (2018), 30(20), n/a, database is CAplus and MEDLINE.

Fluorine-contained polymers, which were widely used in highly efficient polymer solar cells (PSCs), are rather costly due to their complicated synthesis and low yields in the preparation of components. Here, the feasibility of replacing the critical fluorine substituents in high-performance photovoltaic polymer donors with chlorine is demonstrated, and two polymeric donors, PBDB-T-2F and PBDB-T-2Cl, are synthesized and compared in parallel. The synthesis of PBDB-T-2Cl is much simpler than that of PBDB-T-2F. The two polymers have similar optoelectronic and morphol. properties, except the chlorinated polymer possess lower mol. energy levels than the fluorinated one. As a result, the PBDB-T-2Cl-based PSCs exhibit higher open circuit voltage (V_oc) than the PBDB-T-2F-based devices, leading to an outstanding power conversion efficiency of over 14%. This work establishes a more economical design paradigm of replacing fluorine with chlorine for preparing highly efficient polymer donors.

Advanced Materials (Weinheim, Germany) published new progress about 1514905-24-8. 1514905-24-8 belongs to benzothiophene, auxiliary class Organic Photo-Voltaic Materials, OPV,BDT Donors, name is 4,8-Bis(5-(2-ethylhexyl)-4-fluorothiophen-2-yl)benzo[1,2-b:4,5-b’]dithiophene, and the molecular formula is C10H14N2O, SDS of cas: 1514905-24-8.

Referemce:
https://en.wikipedia.org/wiki/Benzothiophene,
Benzothiophene | C8H6S – PubChem

Pan, Bo-Sheng published the artcileAn orally available non-nucleotide STING agonist with antitumor activity, Synthetic Route of 129425-81-6, the publication is Science (Washington, DC, United States) (2020), 369(6506), eaba6098, database is CAplus and MEDLINE.

Pharmacol. activation of the STING (stimulator of interferon genes)-controlled innate immune pathway is a promising therapeutic strategy for cancer. Here we report the identification of MSA-2, an orally available non-nucleotide human STING agonist. In syngeneic mouse tumor models, s.c. and oral MSA-2 regimens were well tolerated and stimulated interferon-β secretion in tumors, induced tumor regression with durable antitumor immunity, and synergized with anti-PD-1 therapy. Exptl. and theor. analyses showed that MSA-2 exists as interconverting monomers and dimers in solution, but only dimers bind and activate STING. This model was validated by using synthetic covalent MSA-2 dimers, which were potent agonists. Cellular potency of MSA-2 increased upon extracellular acidification, which mimics the tumor microenvironment. These properties appear to underpin the favorable activity and tolerability profiles of effective systemic administration of MSA-2.

Science (Washington, DC, United States) published new progress about 129425-81-6. 129425-81-6 belongs to benzothiophene, auxiliary class Inhibitor, name is 4-(5,6-Dimethoxybenzo[b]thiophen-2-yl)-4-oxobutanoic acid, and the molecular formula is C14H14O5S, Synthetic Route of 129425-81-6.

Referemce:
https://en.wikipedia.org/wiki/Benzothiophene,
Benzothiophene | C8H6S – PubChem

Mu, Delong published the artcileEnantioselective synthesis of acyclic monohydrosilanes by steric hindrance assisted C-H silylation, Product Details of C12H14S, the publication is Chemical Communications (Cambridge, United Kingdom) (2022), 58(53), 7388-7391, database is CAplus and MEDLINE.

Herein, a rhodium-catalyzed desymmetrization of dihydrosilanes with heterocyclic compounds via intermol. dehydrogenative C-H silylation is developed. The strategy tolerates a variety of thianaphthene and thiophene derivatives, giving rise to a wide range of silicon-stereogenic acyclic monohydrosilanes. Several rare skeletons featuring bis-silicon-stereogenic centers were also designed to enhance the library’s diversity further. Preliminary mechanistic studies reveal that the surrounding spatial environment of the Si-center plays a crucial role in enabling intermol. C-H silylation preferentially.

Chemical Communications (Cambridge, United Kingdom) published new progress about 17515-00-3. 17515-00-3 belongs to benzothiophene, auxiliary class 5.6_Aromatics,Benzothiophens, name is 5-(tert-Butyl)benzo[b]thiophene, and the molecular formula is C12H14S, Product Details of C12H14S.

Referemce:
https://en.wikipedia.org/wiki/Benzothiophene,
Benzothiophene | C8H6S – PubChem

Ozaki, Kyohei published the artcileAnnulative π-extension (APEX) of heteroarenes with dibenzosiloles and dibenzogermoles by palladium/o-chloranil catalysis, Recommanded Product: 5-(tert-Butyl)benzo[b]thiophene, the publication is Organic Letters (2017), 19(7), 1930-1933, database is CAplus and MEDLINE.

Annulative π-extension (APEX) reactions of heteroarenes are described herein. A catalytic system comprising a cationic palladium species and o-chloranil using dimethyldibenzosiloles as π-extending agents enabled the extension of the π-system of benzo[b]thiophenes. π-Extended dibenzofurans and carbazoles could also be obtained from benzofuran and N-tosylindole, resp., with dimethyldibenzogermole as a germanium-based π-extending agent. Mechanistic investigations indicated two possible reaction pathways involving carbopalladation-based double C-H arylation of benzothiophene or formal cycloaddition/oxidation cascades.

Organic Letters published new progress about 17515-00-3. 17515-00-3 belongs to benzothiophene, auxiliary class 5.6_Aromatics,Benzothiophens, name is 5-(tert-Butyl)benzo[b]thiophene, and the molecular formula is C12H14S, Recommanded Product: 5-(tert-Butyl)benzo[b]thiophene.

Referemce:
https://en.wikipedia.org/wiki/Benzothiophene,
Benzothiophene | C8H6S – PubChem

Wang, Xin published the artcilePalladium-Catalyzed Desymmetric Intermolecular C-N Coupling Enabled by a Chiral Monophosphine Ligand Derived from Anthracene Photodimer, Computed Properties of 177735-30-7, the publication is Organic Letters (2021), 23(14), 5485-5490, database is CAplus and MEDLINE.

An anthracene-photodimer-derived chiral monophosphine ligand I, which features dual chirality and a rigid scaffold was presented. This ligand exhibited remarkable efficiency in Pd-catalyzed desym. intermol. C-N coupling under mild conditions with excellent chemo- and enantioselectivity.

Organic Letters published new progress about 177735-30-7. 177735-30-7 belongs to benzothiophene, auxiliary class Boronic acid and ester,Benzothiophene,Boronic Acids,Boronic acid and ester, name is (1-Benzothiophen-4-yl)boronic acid, and the molecular formula is C8H8O3, Computed Properties of 177735-30-7.

Referemce:
https://en.wikipedia.org/wiki/Benzothiophene,
Benzothiophene | C8H6S – PubChem

Chen, Zhongxin published the artcileEvolution of the electronic structure in open-shell donor-acceptor organic semiconductors, Recommanded Product: 4,8-Bis(5-bromo-4-(2-ethylhexyl)thiophen-2-yl)benzo[1,2-c:4,5-c’]bis[1,2,5]thiadiazole, the publication is Nature Communications (2021), 12(1), 5889, database is CAplus and MEDLINE.

The donor-acceptor organic semiconductors comprised of diketopyrrolopyrrole and naphthobisthiadiazole acceptors and various electron-rich donors commonly utilized in constructing high-performance organic semiconductors were reported. NMR, ESR, magnetic susceptibility measurements, single-crystal X-ray studies and computational investigations connect the bandgap, π-extension, structural and electronic features with the emergence of various degrees of diradical character. This work systematically demonstrates the widespread diradical character in the classical donor-acceptor organic semiconductors and provides distinctive insights into their ground state structure-property relationship.

Nature Communications published new progress about 1401018-41-4. 1401018-41-4 belongs to benzothiophene, auxiliary class Organic Photo-Voltaic Materials, OPV,BT Acceptors, name is 4,8-Bis(5-bromo-4-(2-ethylhexyl)thiophen-2-yl)benzo[1,2-c:4,5-c’]bis[1,2,5]thiadiazole, and the molecular formula is C30H36Br2N4S4, Recommanded Product: 4,8-Bis(5-bromo-4-(2-ethylhexyl)thiophen-2-yl)benzo[1,2-c:4,5-c’]bis[1,2,5]thiadiazole.

Referemce:
https://en.wikipedia.org/wiki/Benzothiophene,
Benzothiophene | C8H6S – PubChem

Zhao, Wenchao published the artcileMolecular Optimization Enables over 13% Efficiency in Organic Solar Cells, COA of Formula: C34H40F2S4, the publication is Journal of the American Chemical Society (2017), 139(21), 7148-7151, database is CAplus and MEDLINE.

A new polymer donor (PBDB-T-SF) and a new small mol. acceptor (IT-4F) for fullerene-free organic solar cells (OSCs) were designed and synthesized. The influences of fluorination on the absorption spectra, mol. energy levels, and charge mobilities of the donor and acceptor were systematically studied. The PBDB-T-SF:IT-4F-based OSC device showed a record high efficiency of 13.1%, and an efficiency of over 12% can be obtained with a thickness of 100-200 nm, suggesting the promise of fullerene-free OSCs in practical applications.

Journal of the American Chemical Society published new progress about 1514905-24-8. 1514905-24-8 belongs to benzothiophene, auxiliary class Organic Photo-Voltaic Materials, OPV,BDT Donors, name is 4,8-Bis(5-(2-ethylhexyl)-4-fluorothiophen-2-yl)benzo[1,2-b:4,5-b’]dithiophene, and the molecular formula is C15H23BO2, COA of Formula: C34H40F2S4.

Referemce:
https://en.wikipedia.org/wiki/Benzothiophene,
Benzothiophene | C8H6S – PubChem