Chapman, Norman Bellamy published the artcilePharmacologically active benzo[b]thiophene derivatives. IV. 5- and 6-Alkyl derivatives with an N-alkyl-N-(2-chloroethyl)aminomethyl group in the 3-position, Product Details of C12H14S, the publication is Journal of the Chemical Society [Section] C: Organic (1968), 514-17, database is CAplus and MEDLINE.
3-Chloromethylbenzo[b]thiophene reacted with N-ethyl-, N-isopropyl-, N-butyl-, N-tert-butyl, or N-benzylethanolamine to give the corresponding N-alkyl – N – (2 – hydroxyethyl) – 3 – aminomethylbenzo[b]thiophene derivatives With SOCl2 in dry CHCl3 these amino alcs. gave the corresponding N-alkyl-N-(2-chloroethyl)-3-aminomethylbenzo[b]thiophene hydrochlorides. A similar range of compounds was obtained from 5- or 6-methylbenzo[b]thiophene but only the N-Et derivative was prepared from 5-ethyl-, 5-isopropyl-, or 5-tert – butylbenzo[b]thiophene. N,N – Bis(2 – hydroxyethyl) – 3-aminomethylbenzo[b]thiophene and its 5-Et derivative were also prepared and converted into the corresponding nitrogen mustards. These compounds were evaluated pharmacol., with special emphasis on their anti-5HT and antitumor activity.
Journal of the Chemical Society [Section] C: Organic published new progress about 17515-00-3. 17515-00-3 belongs to benzothiophene, auxiliary class 5.6_Aromatics,Benzothiophens, name is 5-(tert-Butyl)benzo[b]thiophene, and the molecular formula is C12H14S, Product Details of C12H14S.
Referemce:
https://en.wikipedia.org/wiki/Benzothiophene,
Benzothiophene | C8H6S – PubChem