Fehring, Susan I. published the artcileEffect of the glutathione S-transferase inhibitor, tienilic acid, on biliary excretion of sulfobromophthalein, Product Details of C13H8Cl2O4S, the main research area is tienilate interaction sulfobromophthalein biliary excretion; glutathione transferase inhibitor sulfobromophthalein biliary excretion.
Tienilic acid, a phenoxyacetic acid diuretic, reduces the amount of total sulfobromophthalein (BSP) excretion in the isolated perfused rat liver (IPRL). This reduction was primarily by reduction in excretion of conjugated BSP, with excretion of unchanged BSP being relatively unaffected. TA also reduces the amount of conjugated BSP formed in vitro, indicating that its effect in the IPRL may be by means of inhibiting the glutathione S-transferase enzymes involved in the formation of the conjugate. It would appear that a reduction in the biliary excretion of BSP cannot be taken to be an indication of reduced liver function in a general sense.
Chemico-Biological Interactions published new progress about Bile. 40180-04-9 belongs to class benzothiophene, name is 2-(2,3-Dichloro-4-(thiophene-2-carbonyl)phenoxy)acetic acid, and the molecular formula is C13H8Cl2O4S, Product Details of C13H8Cl2O4S.
Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem