Dayan, J. published the artcileApplication of the SOS chromotest to 10 pharmaceutical agents, Quality Control of 40180-04-9, the main research area is drug mutagenesis SOS chromotest assay.
The SOS function-inducing activity of 10 compounds belonging to different chem. classes was studied in Escherichia coli PQ37. The choice of these chems. was based on previously reported mutagenesis studies. This study indicated that 6 compounds which did not induce a pos. response in the Ames test and other mutagenesis tests were also neg. in the SOS chromotest. The other compounds studied had a pos. response in the SOS-inducing function in addition to the pos. results from the Ames test. In order to establish a correlation between these 2 tests a study requiring a larger selection of chem. agents is needed.
Mutation Research, Genetic Toxicology Testing published new progress about DNA SOS repair. 40180-04-9 belongs to class benzothiophene, name is 2-(2,3-Dichloro-4-(thiophene-2-carbonyl)phenoxy)acetic acid, and the molecular formula is C13H8Cl2O4S, Quality Control of 40180-04-9.
Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem