Kumar, Togiti Uday published the artcileApplication of Polyphosphoric Acid-Mediated Acyl Migration for Regiospecific Synthesis of Diverse 2-Acylpyrroles from Chalcones, Formula: C6H6OS, the main research area is chalcone preparation toluenesulfonylmethyl isocyanide Van Leusen reaction; acylpyrrole preparation polyphosphoric acid catalyst regioselective intermol transacylation.
A metal-free approach for the synthesis of 2-acylpyrroles was reported. Synthesis of the target mol. started from chalcones and carried out in two steps. Initial step involved the conversion of chalcones to corresponding 4-substituted-3-acylpyrroles by reaction with TosMIC. In the subsequent step, target mols. were obtained in modest to good yields by polyphosphoric acid-mediated acyl rearrangement of 3-acylpyrroles to their 2-acyl congeners. The crucial final step was amenable to diverse substitutions on pyrrole ring. Preliminary experiment for the determination of mechanism indicated the involvement of acylium ion.
Journal of Heterocyclic Chemistry published new progress about Aldehydes Role: RCT (Reactant), RACT (Reactant or Reagent). 1468-83-3 belongs to class benzothiophene, name is 3-Acetylthiophene, and the molecular formula is C6H6OS, Formula: C6H6OS.
Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem