Amberchan, Gabriella published the artcileReaction of Diisobutylaluminum Borohydride, a Binary Hydride, with Selected Organic Compounds Containing Representative Functional Groups, Related Products of benzothiophene, the main research area is alc preparation; amine tertiary preparation; tertiary amide reduction diisobutylaluminum borohydride preparation; aldehyde reduction diisobutylaluminum borohydride preparation; epoxide reduction diisobutylaluminum borohydride preparation; carboxylic acid reduction diisobutylaluminum borohydride preparation; ester reduction diisobutylaluminum borohydride preparation; secondary alc preparation; ketone reduction diisobutylaluminum borohydride preparation; primary amine preparation; nitrile reduction diisobutylaluminum borohydride preparation.
The binary hydride, diisobutylaluminum borohydride [(iBu)2AlBH4], synthesized from diisobutylaluminum hydride (DIBAL) and borane di-Me sulfide (BMS) has shown great potential in reducing a variety of organic functional groups. This unique binary hydride, (iBu)2AlBH4, is readily synthesized, versatile, and simple to use. Aldehydes e.g., benzaldehyde, ketones e.g., 2-octanone, esters e.g., Et 3-phenylpropionate, and epoxides e.g., cyclohexeneoxide are reduced very fast to the corresponding alcs. viz., benzyl alc., 2-octanol, 3-phenylpropan-1-ol and cyclohexanol resp. in essentially quant. yields. This binary hydride can reduce tertiary amides e.g., N,N-diethylbenzamide rapidly to the corresponding amine, N,N-diethylbenzylamine at 25°C in an efficient manner. Furthermore, nitriles e.g., benzonitrile are converted into the corresponding amine, 4-methylbenzyl amine in essentially quant. yields. These reactions occur under ambient conditions and are completed in an hour or less. The reduction products are isolated through a simple acid-base extraction and without the use of column chromatog. Further investigation showed that (iBu)2AlBH4 has the potential to be a selective hydride donor as shown through a series of competitive reactions. Similarities and differences between (iBu)2AlBH4, DIBAL, and BMS are discussed.
Journal of Organic Chemistry published new progress about Aldehydes Role: RCT (Reactant), RACT (Reactant or Reagent). 1468-83-3 belongs to class benzothiophene, name is 3-Acetylthiophene, and the molecular formula is C6H6OS, Related Products of benzothiophene.
Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem