Vigneswaran, Vipulan published the artcileBeta-amino phosphine Mn catalysts for 1,4-transfer hydrogenation of chalcones and allylic alcohol isomerization, Safety of 3-Acetylthiophene, the main research area is amino phosphine Mn catalyst preparation transfer hydrogenation chalcone isomerization; transfer hydrogenation chalcone allylic alc isomerization.
Mn complexes with amino acid derived PN ligands were used in the catalytic transfer hydrogenation (TH) of ketone and chalcone substrates in 2-propanol with mild heating. Moreover, chalcones are reduced selectively to the saturated ketone at short times and can be fully converted to the alc. when reactions are prolonged. The mechanism of chalcone reduction was briefly considered. Allylic alcs. are not reactive in 2-propanol, but quant. isomerization occurs in toluene. Thus, we suspect that the allylic alcs. are dehydrogenated and the resulting ketone is formed through a direct 1,4-hydrogenation of the chalcone. Finally, several other related ligands that have been used in Mn-based TH reactions were explored to test the viability of ligand design in favoring chemoselectivity. The β-amino phosphine ligands proved most effective in this regard. Mn complexes with amino acid-derived PN ligands were used to enact catalytic transfer hydrogenation (TH) of ketone and chalcone substrates in 2-proponal with mild heating. Moreover, chalcones are reduced selectively to the saturated ketone at short times and can be fully converted to the alc. under prolonged reactions. The mechanism of chalcone reduction was briefly considered. Allylic alcs. are not reactive in 2-proponal, but quant. isomerization occurs in toluene. Thus, we suspect that the allylic alcs. are dehydrogenated and the resulting ketone is formed through a direct 1,4-hydrogenation of the chalcone. Finally, several other related ligands that have been used in Mn-based TH reactions were explored to test the viability of ligand design in favoring chemoselectivity. The beta-amino phosphine ligands proved most effective in this regard.
Organometallics published new progress about Allylic alcohols Role: RCT (Reactant), RACT (Reactant or Reagent). 1468-83-3 belongs to class benzothiophene, name is 3-Acetylthiophene, and the molecular formula is C6H6OS, Safety of 3-Acetylthiophene.
Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem