Day: November 14, 2022

Duong, Uyen T. published the artcileReactivity of Carbenes in Aqueous Nanomicelles Containing Palladium Nanoparticles, Product Details of C6H6OS, the main research area is palladium nanoparticle aqueous nanomicelle nanocatalyst.

Palladium nanoparticles ligated with inexpensive triphenylphosphine and amphiphile PS-750-M are suitable for exploring the reactivity of carbenes in aqueous nanomicelles. Nanocatalyst is highly selective for metal-carbene migratory insertion, and micelle of PS-750-M shields the in situ generated carbene to prevent the dimerization. In addition to a broad substrate scope, the nanocatalyst is thoroughly characterized by NMR, SEM, high-resolution transmission electron microscopy, XPS, and thermogravimetric anal. The sustainability of the reaction system is demonstrated by the recyclability of both the catalyst and the micellar reaction medium at variable reaction scales. NMR and kinetics studies with the recycled catalyst revealed the retention of catalyst integrity. Control experiments including the dynamic light scattering study demonstrate the importance of PS-750-M.

ACS Catalysis published new progress about Aryl bromides Role: RCT (Reactant), RACT (Reactant or Reagent). 1468-83-3 belongs to class benzothiophene, name is 3-Acetylthiophene, and the molecular formula is C6H6OS, Product Details of C6H6OS.

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Ibrahim, Jessica Juweriah published the artcileEfficient Transfer Hydrogenation of Ketones Catalyzed by a Phosphine-Free Cobalt-NHC Complex, Synthetic Route of 1468-83-3, the main research area is ketone transfer hydrogenation cobalt NHC complex catalyst.

A simple phosphine-free cobalt-NHC pincer complex was synthesized and used for the transfer hydrogenation of ketones with 2-propanol as hydrogen donor. A broad range of ketones varying from aromatic, aliphatic and heterocyclic were effectively reduced to their corresponding alcs. in moderate to excellent yields with good tolerance of functional groups.

European Journal of Organic Chemistry published new progress about Alcohols Role: SPN (Synthetic Preparation), PREP (Preparation). 1468-83-3 belongs to class benzothiophene, name is 3-Acetylthiophene, and the molecular formula is C6H6OS, Synthetic Route of 1468-83-3.

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Xiao, Zihui published the artcileElectrochemical reduction of functionalized carbonyl compounds: enhanced reactivity over tailored nanoporous gold, Application In Synthesis of 1468-83-3, the main research area is reusable nanoporous gold catalyst preparation pore size carbonyl reduction; carbonyl compound diphenylsilane gold nanocatalyst electrochem reduction chemoselective; alc preparation.

The effect of the pore size of nanoporous gold (NPG) on electrochem. reduction of functionalized carbonyl compounds was investigated. NPG with a pore size of ∼30 nm significantly enhanced the reactivity with high chemoselectivity at a low-potential. Typically, p-nitrobenzaldehyde reduction demonstrated a high turnover frequency (TOF) up to 232000 h-1.

Nanoscale published new progress about Alcohols Role: SPN (Synthetic Preparation), PREP (Preparation). 1468-83-3 belongs to class benzothiophene, name is 3-Acetylthiophene, and the molecular formula is C6H6OS, Application In Synthesis of 1468-83-3.

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Li, Wei published the artcileDesign of Ru(II)-NHC-Diamine Precatalysts Directed by Ligand Cooperation: Applications and Mechanistic Investigations for Asymmetric Hydrogenation, Name: 3-Acetylthiophene, the main research area is ruthenium heterocyclic carbene complex diamine precatalyst preparation; isocoumarin benzothiophene dioxide ketone enantioselective hydrogenation.

A modular synthesis of Ru(II)-NHC-diamine complexes from readily available chiral N-heterocyclic carbenes (NHCs) and chiral diamines is disclosed for the first time. The well-defined Ru(II)-NHC-diamine complexes show unique structure and coordination chem. including an unusual tridentate coordination effect of 1,2-diphenylethylenediamine. The isolated air-and moisture-stable Ru(II)-NHC-diamine complexes act as versatile precatalysts for the asym. hydrogenation of isocoumarins, benzothiophene 1,1-dioxides, and ketones. Moreover, based on the identification of reaction intermediates by stoichiometric reactions and NMR experiments, together with the DFT calculations, a possible catalytic cycle was proposed.

Journal of the American Chemical Society published new progress about Alcohols Role: SPN (Synthetic Preparation), PREP (Preparation). 1468-83-3 belongs to class benzothiophene, name is 3-Acetylthiophene, and the molecular formula is C6H6OS, Name: 3-Acetylthiophene.

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Ni, Penghui published the artcileA Three-Component Strategy for Benzoselenophene Synthesis under Metal-Free Conditions Using Selenium Powder, Recommanded Product: 3-Acetylthiophene, the main research area is three component indole acetophenone selenium; benzoselenophene preparation.

An efficient three-component benzoselenophenes formation has been developed from substituted indoles, acetophenones, and selenium powder under metal-free conditions. 2-Aryl indoles played an important role to promote benzoselenophene formation from acetophenone derivatives and selenium powder. One C-C and two C-Se bonds were selectively formed to provide 40 new benzoselenophenes in good yields.

Organic Letters published new progress about Acetophenones Role: RCT (Reactant), RACT (Reactant or Reagent). 1468-83-3 belongs to class benzothiophene, name is 3-Acetylthiophene, and the molecular formula is C6H6OS, Recommanded Product: 3-Acetylthiophene.

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Stumpf, Andreas published the artcileSynthesis of 3-Aryl-Substituted 4-Aminopyrazoles from Acetophenones, Synthetic Route of 1468-83-3, the main research area is aryl substituted aminopyrazole preparation; acetophenone oximation condensation.

A synthetic methodol. for a protecting-group-free formation of 3-aryl-substituted 4-aminopyrazoles I [R = 4-MeOC6H4, 3-pyridyl, 3-thienyl, etc.] from acetophenones via a telescoped oximation and hydrazine condensation of 1,3-ketoaldehydes to generate nitrosopyrazoles, and copper-catalyzed NaBH4 reduction of the nitroso group, was demonstrated. The synthesis tolerated a broad scope of substrates with a variety of substituents on the Ph ring to afford the desired products.

Synthesis published new progress about Acetophenones Role: RCT (Reactant), RACT (Reactant or Reagent). 1468-83-3 belongs to class benzothiophene, name is 3-Acetylthiophene, and the molecular formula is C6H6OS, Synthetic Route of 1468-83-3.

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Nori, Divakara Lsomayajulu published the artcileOptimized synthesis of active 5-benzylidine-1,3-thiazolidine- 2,4-dione derivatives, Recommanded Product: 3-Acetylthiophene, the main research area is benzylidene thiazolidinedione preparation; dioxothiazolidinylidenylmethyl benzaldehyde acetophenone condensation.

The active substrates 5-benzylidine-1,3-thiazolidine-2,4-dione derivatives which are a class of α- glucosidase inhibitors was prepared from 4-((Z)-(2,4-dioxothiazolidin-5-ylidene)methyl)benzaldehyde with aromatic/ hetero aromatic ketones in presence of potassium hydroxide with ethanol as solvent. In order to improve the yields the synthesis of 5-benzylidine-1,3-thiazolidine-2,4-dione derivatives were optimized by screening different bases and solvents. Finally better conditions for preparation of these derivatives were established by Quality by design. The 5-benzylidine-1,3-thiazolidine-2,4-dione derivatives were prepared with excellent yield.

Journal of Applicable Chemistry (Lumami, India) published new progress about Acetophenones Role: RCT (Reactant), RACT (Reactant or Reagent). 1468-83-3 belongs to class benzothiophene, name is 3-Acetylthiophene, and the molecular formula is C6H6OS, Recommanded Product: 3-Acetylthiophene.

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Rastogi, Gaurav K. published the artcileDiastereoselective sp3-C-H Functionalization of Arylmethyl Ketones and Transformation of E- to Z-Products Through Photocatalysis, Synthetic Route of 1468-83-3, the main research area is enedione diastereoselective synthesis arylmethyl ketone photocatalyzed transformation.

We have developed an efficient metal-free route for the synthesis of 1,4-enedione derivatives under microwave irradiation by reacting easily available arylmethylketones with DMSO or di-Ph sulfoxide in the presence of TBAI and persulfate. The reaction is very clean and completes within very short time. All the reagents and catalysts are cheap and environmentally benign. In addition, the E-isomer of the products can easily be transformed into the Z-isomer by using eosin Y photocatalyst under the irradiation of white CFL.

European Journal of Organic Chemistry published new progress about Acetophenones Role: RCT (Reactant), RACT (Reactant or Reagent). 1468-83-3 belongs to class benzothiophene, name is 3-Acetylthiophene, and the molecular formula is C6H6OS, Synthetic Route of 1468-83-3.

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Nayak, Soukhyarani G. published the artcileNovel pyrazole-clubbed thiophene derivatives via Gewald synthesis as antibacterial and anti-inflammatory agents, Product Details of C6H6OS, the main research area is pyrazolyl thiophene carbonitrile Schiff base preparation antibacterial antiinflammatory antitubercular; Gewald reaction; Schiff bases; anti-inflammatory; antimicrobial; antitubercular.

The aim of this study was to synthesize newer potent Schiff bases I (R = H, Cl; Ar = 4-fluorophenyl, 3-bromophenyl, 3-thienyl, etc.) by condensing 2-amino-5-(2,4-dichlorophenyl)thiophene-3-carbonitrile and 1,3-disubstituted-1H-pyrazole-4-carbaldehydes II, and to investigate their biol. activity. The compounds I were synthesized via Gewald synthesis and characterized by spectral data and elemental analyses. They were screened for their in vitro antibacterial and anti-inflammatory activities. The synthesized compounds I were also evaluated for in vitro antitubercular activity against Mycobacterium tuberculosis H37Rv using the microplate Alamar Blue assay. Compounds I (R = H, Ar = 4-chlorophenyl; R = H, Ar = 4-fluorophenyl; R = H, Ar = 4-methoxyphenyl; R = H, Ar = 4-methylphenyl; R = Cl, Ar = 4-fluorophenyl; R = Cl, Ar = 4-methoxyphenyl; R = Cl, Ar = 4-methylphenyl) showed promising antibacterial activity. The interactions between the substituted pyrazoles and bovine protein showed promising anti-inflammatory activity. The exptl. results revealed compound I (R = H; Ar = Ph) as a promising antitubercular agent. Hemolytic assays confirmed that the compounds are nontoxic, with percentage hemolysis ranging from 3.6 to 20.1, at a concentration of 1 mg/mL. The results suggest that the pyrazole ring and the substitution pattern on the heterocyclic moiety I have an effect on the bioactivity.

Archiv der Pharmazie (Weinheim, Germany) published new progress about Acetophenones Role: RCT (Reactant), RACT (Reactant or Reagent). 1468-83-3 belongs to class benzothiophene, name is 3-Acetylthiophene, and the molecular formula is C6H6OS, Product Details of C6H6OS.

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem

Geng, Xiao published the artcileIodine-Promoted N-H/α,β-C(sp3)-Trifunctionalization of L-Proline: Access to 3,4-Dihydrobenzo[b][1,7]naphthyridines via Consecutive Decarboxylation/Ring Opening/Dicyclization, Quality Control of 1468-83-3, the main research area is iodine trifunctionalization proline; consecutive decarboxylation ring opening dicyclization; dihydrobenzonaphthyridine preparation green chem.

A N-H/α,β-C(sp3)-trifunctionalization of L-proline, proceeding through an iodine-promoted consecutive decarboxylation/ring-opening/dicyclization process, is achieved. This strategy affords structurally diverse fused N-heterocycles in good yields with a wide substrate scope. Preliminary mechanistic studies indicate that catabolism of L-proline might be involved in this cascade reaction and the in situ generated intermediate 4-aminobutanal was identified as the key intermediate. Notably, this domino strategy enriches the reactivity of versatile L-proline in the synthesis of fused heterocycles.

Organic Letters published new progress about Acetophenones Role: RCT (Reactant), RACT (Reactant or Reagent). 1468-83-3 belongs to class benzothiophene, name is 3-Acetylthiophene, and the molecular formula is C6H6OS, Quality Control of 1468-83-3.

Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem