Ning, Yongquan published the artcileAg-Catalyzed Insertion of Alkynyl Carbenes into C-C Bonds of β-Ketocarbonyls: A Formal C(sp2) Insertion, Formula: C6H6OS, the main research area is allenyl diketone preparation; diketone insertion alkynyl carbene alkynyl nosyl hydrazone silver catalyst.
Herein, a silver-catalyzed alkynyl carbene insertion into β-ketocarbonyls I (R1 = R3 = Me, Et, Ph, 4-t-BuC6H4, 3-thienyl, etc., R2 = H; R1 = Ph, R2 = H, R3 = Me, 4-F3CC6H4; R1 = R3 = Me, R2 = Me, Et, PhCH2; etc.) using alkynyl N-nosylhydrazones II [R4 = cyclopropyl, Cl(CH2)3, Ph, 3-MeOC6H4, 3,5-Cl2C6H3, 2-naphthyl, 1-cyclohexen-1-yl, etc.; Ns = 2-nitrophenylsulfonyl] as alkynyl carbene precursors, which provides access to trisubstituted allenyl ketones III, is reported. This reaction represents the first example of an alkynyl carbene insertion into a C-C σ bond, affording products homologated with an sp2 carbon center. The products are useful substrates for further transformations. Exptl. investigations and theor. calculations suggest the reaction proceeds through a stepwise enol cyclopropanation/retro-aldol pathway.
Organic Letters published new progress about Allenes Role: SPN (Synthetic Preparation), PREP (Preparation). 1468-83-3 belongs to class benzothiophene, name is 3-Acetylthiophene, and the molecular formula is C6H6OS, Formula: C6H6OS.
Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem