Geng, Xiao published the artcileIodine-Promoted N-H/α,β-C(sp3)-Trifunctionalization of L-Proline: Access to 3,4-Dihydrobenzo[b][1,7]naphthyridines via Consecutive Decarboxylation/Ring Opening/Dicyclization, Quality Control of 1468-83-3, the main research area is iodine trifunctionalization proline; consecutive decarboxylation ring opening dicyclization; dihydrobenzonaphthyridine preparation green chem.
A N-H/α,β-C(sp3)-trifunctionalization of L-proline, proceeding through an iodine-promoted consecutive decarboxylation/ring-opening/dicyclization process, is achieved. This strategy affords structurally diverse fused N-heterocycles in good yields with a wide substrate scope. Preliminary mechanistic studies indicate that catabolism of L-proline might be involved in this cascade reaction and the in situ generated intermediate 4-aminobutanal was identified as the key intermediate. Notably, this domino strategy enriches the reactivity of versatile L-proline in the synthesis of fused heterocycles.
Organic Letters published new progress about Acetophenones Role: RCT (Reactant), RACT (Reactant or Reagent). 1468-83-3 belongs to class benzothiophene, name is 3-Acetylthiophene, and the molecular formula is C6H6OS, Quality Control of 1468-83-3.
Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem