Chen, Dongdong published the artcileDomino synthetic strategy for tetrahydrothiophene derivatives from 2-acetylfuran/2-acetylthiophene, benzaldehydes, and sulfur powder, COA of Formula: C6H6OS, the main research area is tetrahydrothiophene preparation diastereoselective; acetylfuran benzaldehyde sulfur domino; acetylthiophene benzaldehyde sulfur domino.
A domino reaction from 2-acetylfuran/2-acetylthiophene, benzaldehydes and sulfur powder was developed to synthesize a series of tetrahydrothiophene derivatives I [R = H, 4-F, 4-Ph, etc.; X = O,S]. The reaction proceeded well to construct five new bonds and a tetrahydrothiophene ring by one-pot. A possible mechanism was proposed, involving a stepwise of Aldol/double Michael addition/internal SN2 cascaded reaction with sulfur powder acts as a source of sulfur. This method was characterized by mild reaction conditions, com. available starting materials and transition-metal-free.
Arabian Journal of Chemistry published new progress about Benzaldehydes Role: RCT (Reactant), RACT (Reactant or Reagent). 1468-83-3 belongs to class benzothiophene, name is 3-Acetylthiophene, and the molecular formula is C6H6OS, COA of Formula: C6H6OS.
Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem