Zhong, Rui published the artcileA Practical and Stereoselective In Situ NHC-Cobalt Catalytic System for Hydrogenation of Ketones and Aldehydes, Formula: C6H6OS, the main research area is cobalt complex catalyst preparation; secondary alc primary preparation diastereoselective; ketone hydrogenation cobalt catalyst; aldehyde hydrogenation cobalt catalyst.
Herein, a practical in situ catalytic system generated by easily available pincer NHC precursors, CoCl2 and a base enabled efficient and high-yielding hydrogenation of a broad range of ketones and aldehydes (over 50 examples and a maximum turnover number [TON] of 2,610) to afford alcs. was reported. This was the first example of NHC-Co-catalyzed hydrogenation of C=O bonds using flexible pincer NHC ligands consisting of a N-H substructure. Diastereodivergent hydrogenation of substituted cyclohexanone derivatives was also realized by fine-tuning of the steric bulk of pincer NHC ligands. Addnl., a bis(NHCs)-Co complex was successfully isolated and fully characterized and it exhibited excellent catalytic activity that equals that of the in-situ-formed catalytic system.
Chem published new progress about Alcohols Role: PRP (Properties), SPN (Synthetic Preparation), PREP (Preparation). 1468-83-3 belongs to class benzothiophene, name is 3-Acetylthiophene, and the molecular formula is C6H6OS, Formula: C6H6OS.
Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem