Xu, Jun published the artcileOxidative Sulfonylation of Hydrazones Enabled by Synergistic Copper/Silver Catalysis, COA of Formula: C6H6OS, the main research area is ketosulfone acylsulfonamide preparation; hydrazone sulfinate oxidative sulfonylation copper silver catalyst.
A copper/silver-cocatalyzed protocol for oxidative sulfonylation of hydrazones with sodium sulfinates was demonstrated. A wide range of β-ketosulfones RC(O)CH(R1)SO2R2 [R = c-hexyl, Ph, 4-FC6H4, etc.; R1 = H, Me, Et, etc.; R2 = Et, Ph, 2-thienyl, etc.] and N-acylsulfonamides R3C(O)N(R4)(SO2Ph) [R3 = c-hexyl, Ph, 2-FC6H4, etc; R4 = morpholino] were directly synthesized in moderate to good yields. This work provided a viable method for scalable preparation of β-ketosulfone derivatives that have found wide applications in the pharmaceutical industry.
Journal of Organic Chemistry published new progress about Ketones Role: PRP (Properties), RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 1468-83-3 belongs to class benzothiophene, name is 3-Acetylthiophene, and the molecular formula is C6H6OS, COA of Formula: C6H6OS.
Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem