Shen, Cong published the artcileAccess to axially chiral aryl 1,3-dienes by transient group directed asymmetric C-H alkenylations, Category: benzothiophene, the main research area is axially chiral aryl diene preparation; styrene olefin palladium catalyst asym CH alkenylation.
Herein presented, a Pd-catalyzed atroposelective preparation of aryl 1,3-dienes from readily available styrenes and olefins through an aldehyde derived transient chiral auxiliary, proceeding by enantioselective olefinic C-H alkenylation of styrenes via seven-membered endo-cyclometallation. The generality of the protocol was demonstrated by the smooth conversion of a wide range of 2-vinyl benzaldehyde derivatives to afford up to 99% yields and high to excellent enantioselectivities (up to >99% ee). The derived axially chiral carboxylic acid was demonstrated to be a more efficient ligand in the Cp*Co(III)-catalyzed asym. C(sp3)-H alkylation.
Organic Chemistry Frontiers published new progress about Alkenes Role: PRP (Properties), RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 1468-83-3 belongs to class benzothiophene, name is 3-Acetylthiophene, and the molecular formula is C6H6OS, Category: benzothiophene.
Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem