Schmalzbauer, Matthias published the artcileRedox-Neutral Photocatalytic C-H Carboxylation of Arenes and Styrenes with CO2, Recommanded Product: 3-Acetylthiophene, the main research area is aryl carboxylic acid preparation; arene carbon dioxide redox neutral photocatalytic CH carboxylation; cinnamic acid diastereoselective preparation; styrene carbon dioxide redox neutral photocatalytic CH carboxylation.
A redox-neutral CH carboxylation of arenes and styrenes using a photocatalytic approach was described for the synthesis of aryl/unsaturated-carboxylic acids RCOOH [R = 1-naphthyl, CH=CHPh, 5-cyano-2-thienyl, etc.]. Upon blue-light excitation, the anthrolate anion photocatalyst was able to reduce many aromatic compounds to their corresponding radical anions, which react with CO2 to afford carboxylic acids. High-throughput screening and computational anal. suggest that a correct balance between electron affinity and nucleophilicity of substrates was essential. This novel methodol. enabled the carboxylation of numerous aromatic compounds, including many that were not tolerated in classical carboxylation chem. Over 50 examples of CH functionalizations using CO2 or ketones illustrated a broad applicability.
Chem published new progress about Carboxylation. 1468-83-3 belongs to class benzothiophene, name is 3-Acetylthiophene, and the molecular formula is C6H6OS, Recommanded Product: 3-Acetylthiophene.
Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem