In 2019,Advanced Synthesis & Catalysis included an article by Xu, Xuefeng; Zhou, Zhi; Wang, Zhipin; Ma, Xinna; Chen, Xin; Zhang, Xu; Yu, Xiyong; Yi, Wei. Related Products of 88-15-3. The article was titled 《Cobalt(III)-Catalyzed and Dimethyl Sulfoxide-Involved Cross-Coupling of Ketones and Amides for Direct Synthesis of β-Amino Ketones》. The information in the text is summarized as follows:
A straightforward synthesis of β-amino ketones I [R1 = Ph, 2-naphthyl, 4-FC6H4, etc.; R2 = Ph, 4-MeC6H4, 3-MeOC6H4, 3-FC6H4] and II [R3 = Cp, Cy, Ph, etc.] via cobalt(III)-catalyzed and DMSO-involved cross-coupling reaction of ketones and amides as the substrates was reported. The results came from multiple reactions, including the reaction of 1-Thiophen-2-yl-ethanone(cas: 88-15-3Related Products of 88-15-3)
1-Thiophen-2-yl-ethanone(cas: 88-15-3) belongs to thiophenes. Specialized thiophenes can be synthesized similarly using Lawesson’s reagent as the sulfidizing agent, or via the Gewald reaction, which involves the condensation of two esters in the presence of elemental sulfur. Another method is the Volhard–Erdmann cyclization. Related Products of 88-15-3
Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem