The author of 《PTSA-Catalyzed Reaction of Alkyl/Aryl Methyl Ketones with Aliphatic Alcohols in the Presence of Selenium Dioxide: A Protocol for the Generation of an α-Ketoacetals Library》 were Shangpliang, O. Risuklang; Wanniang, Kmendashisha; Kshiar, Baskhemlang; Marpna, Ibakyntiew D.; Lipon, Tyrchain Mitre; Mizar, Pushpak; Myrboh, Bekington. And the article was published in ACS Omega in 2019. Application of 88-15-3 The author mentioned the following in the article:
A novel approach has been developed for the synthesis of a wide range of α-ketoacetals by the reaction of alkyl/aryl Me ketones and aliphatic alcs. in presence of selenium dioxide catalyzed by p-toluenesulfonic acid (PTSA). This method represents a general route to obtain a wide variety of α-ketoacetals in a simple, rapid and practical manner. This approach is particularly attractive because of the easily availability of the starting materials, mild reaction temperature and good yields of the products. The resulting α-ketoacetals are of much synthetic value as organic intermediates. In addition to this study using 1-Thiophen-2-yl-ethanone, there are many other studies that have used 1-Thiophen-2-yl-ethanone(cas: 88-15-3Application of 88-15-3) was used in this study.
1-Thiophen-2-yl-ethanone(cas: 88-15-3) belongs to thiophenes. Reflecting their high stabilities, thiophenes arise from many reactions involving sulfur sources and hydrocarbons, especially unsaturated ones. Thiophenes are classically prepared by the reaction of 1,4-diketones, diesters, or dicarboxylates with sulfidizing reagents such as P4S10 such as in the Paal-Knorr thiophene synthesis. Application of 88-15-3
Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem