《Palladium-carbene catalyzed direct arylation of five-membered heteroaromatics》 was written by Kaloglu, Murat; Kaloglu, Nazan; Yildirim, Ilkay; Ozdemir, Namik; Ozdemir, Ismail. Computed Properties of C6H6OS And the article was included in Journal of Molecular Structure in 2020. The article conveys some information:
In this study, PEPPSI-type, (PEPPSI = Pyridine Enhanced Precatalyst Preparation Stabilization and Initiation), new Pd-catalysts with N-heterocyclic carbene ligand I [R1 = Ph, 4-MeC6H4, 2,4,6-(Me)3C6H2, etc.; R2 = nBu, 3-MeOC6H4; X = Cl, Br] were synthesized and used as catalysts in the synthesis of bi(hetero)arenes R3-R4 [R3 = 5-acetyl-2-thienyl, furan-2-carbonyl, 4,5-dimethyl-thiazolyl; R4 = Ph, 4-MeC6H4, 3-quinolyl, etc.] by direct arylation process. The structures of complexes I were elucidated by different spectroscopic and anal. techniques such as NMR, FT-IR and elemental anal. The more detailed structural characterization of one of the complexes I [R1 = 4-MeC6H4; R2 = 3-MeOC6H4; X = Br] was determined by single-crystal X-ray diffraction study. Complexes I were used as effective catalysts in the direct arylation of five-membered heteroaromatics such as thiophene, furan and thiazole derivatives with aryl bromides in the presence of 1 mol% of catalyst loading and successful results were obtained. In the experimental materials used by the author, we found 1-Thiophen-2-yl-ethanone(cas: 88-15-3Computed Properties of C6H6OS)
1-Thiophen-2-yl-ethanone(cas: 88-15-3) belongs to thiophenes. Reflecting their high stabilities, thiophenes arise from many reactions involving sulfur sources and hydrocarbons, especially unsaturated ones. Thiophenes are classically prepared by the reaction of 1,4-diketones, diesters, or dicarboxylates with sulfidizing reagents such as P4S10 such as in the Paal-Knorr thiophene synthesis. Computed Properties of C6H6OS
Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem