COA of Formula: C6H6OSIn 2020 ,《Design, molecular docking, synthesis and biological evaluation of novel 2,5-substituted imidazole derivatives as anti-inflammatory agents》 was published in International Journal of Pharma and Bio Sciences. The article was written by Monalika, Akepogu; Bhargavi, M. Vijaya. The article contains the following contents:
In the current study 2,5-disubstituted imidazoles were synthesized starting from 2-acetyl thiophene. All the synthesized imidazoles were subjected to insilico docking studies (PDB ID:1N26) using AUTODOCK vina software. All the synthesized derivatives were evaluated for invitro anti-inflammatory activity. The experimental part of the paper was very detailed, including the reaction process of 1-Thiophen-2-yl-ethanone(cas: 88-15-3COA of Formula: C6H6OS)
1-Thiophen-2-yl-ethanone(cas: 88-15-3) belongs to thiophenes. Reflecting their high stabilities, thiophenes arise from many reactions involving sulfur sources and hydrocarbons, especially unsaturated ones. Thiophenes are classically prepared by the reaction of 1,4-diketones, diesters, or dicarboxylates with sulfidizing reagents such as P4S10 such as in the Paal-Knorr thiophene synthesis. COA of Formula: C6H6OS
Referemce:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem