So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic.Verma, Piyush Kumar; Prasad, K. Sujit; Varghese, Dominic; Geetharani, K. researched the compound: Methyl 3-bromopropanoate( cas:3395-91-3 ).Application of 3395-91-3.They published the article 《Cobalt(I)-Catalyzed Borylation of Unactivated Alkyl Bromides and Chlorides》 about this compound( cas:3395-91-3 ) in Organic Letters. Keywords: cobalt catalyzed borylation unactivated alkyl bromide chloride diboron reagent; alkyl boronic ester preparation. We’ll tell you more about this compound (cas:3395-91-3).
A Co-complex-catalyzed borylation of a wide range of alkyl halides with a diboron reagent (B2pin2 or B2neop2) was developed under mild reaction conditions, demonstrating the 1st Co-mediated cross-coupling with alkyl electrophiles. This protocol allows alkyl boronic esters to be accessed from alkyl halides, including alkyl chlorides, which were used rarely as coupling partners. Mechanistic studies reveal the possible involvement of an alkyl radical intermediate in this Co-mediated catalytic cycle.
I hope my short article helps more people learn about this compound(Methyl 3-bromopropanoate)Application of 3395-91-3. Apart from the compound(3395-91-3), you can read my other articles to know other related compounds.
Reference:
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem