Reference of 35212-85-2, New research progress on 35212-85-2 in 2021. The transformation of simple hydrocarbons into more complex and valuable products via catalytic C–H bond functionalisation has revolutionised modern synthetic chemistry. In a article, 35212-85-2, molcular formula is C10H9NO2S, introducing its new discovery.
The title compound 5 is synthesized by the reaction of the potassium salt of 3-aminobenzothiophene-2-carboxylic acid with phosgene.Compound 5 is readily alkylated to give 6 with methyl iodide, benzyl bromide, or propargyl bromide in the presence of sodium hydride.Reaction of 5 and 6 with nucleophiles follows specifically different pathways.Compound 5 is readily ionized to the isocyanate species 13 and subsequently reacts with methanol or methylamine to produce exclusively the carbamate 7 or ureido acid 9.The N-substituted derivative 6, in analogous reaction withmethanol or methylamine, produce exclusively the amino ester 8 or the amino amide 10.The N-benzyl derivative 6b reacts with the cyclic S-methylthiopseudourea 11 to give the tetracycle 12, a new ring system.
In conclusion, we affirm that quantitative kinetic descriptions of catalytic behavior continue to navigate research efforts intended to implement such knowledge in the development of new catalytic chemistries. Read on for other articles about 35212-85-2. Reference of 35212-85-2
Reference：
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem