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The octanol-water partition coefficients (log P) for a series of benzo[b]thiophenes were estimated by high performance liquid chromatography on a C18 reversed-phase column, using methanol-water as mobile phase. Measured values for the benzo[b]thiophenes ranged from 2.08 to 4.18. The experimental log P values showed good correlation with those predicted by the Dixon’s method.
Therefore, this conceptually novel strategy might open impressive avenues to establish green and sustainable chemistry platforms.In my other articles, you can also check out more blogs about 22913-24-2. Reference of 22913-24-2
Reference：
Benzothiophene – Wikipedia,
Benzothiophene | C8H6S – PubChem